Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection

Y Wan, DG Anastasakis, J Rodriguez, M Palangat… - Cell, 2021 - cell.com
The activities of RNA polymerase and the spliceosome are responsible for the heterogeneity
in the abundance and isoform composition of mRNA in human cells. However, the dynamics …

Bioinformatic, genomic and evolutionary analysis of genes: A case study in dipteran CSPs

JF Picimbon - Methods in enzymology, 2020 - Elsevier
Understanding physiological tasks may start by a good understanding of evolutionary traits
in a given protein gene family. The successful completion of various genome projects is a …

De novo emergence and potential function of human-specific tandem repeats in brain-related loci

K Kim, S Bang, DA Yoo, H Kim, S Suzuki - Human Genetics, 2019 - Springer
Tandem repeats (TRs) are widespread in the genomes of all living organisms. In eukaryotes,
they are found in both coding and noncoding regions and have potential roles in the …

真核生物基因组长内含子递归剪接事件的分子机制

魏金川, 徐添翼, 吴静, 宋晓峰 - 遗传, 2019 - chinagene.cn
在高等真核生物基因组转录过程中, 一次剪接可完成短内含子的去除, 而较长内含子(> 10 kb)
则需通过多次剪接方可去除. 多次剪接去除长内含子的过程通常被称为递归性剪接 …