Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of
activities. The combination of different pharmacophores in a pyrrole ring system has led to …

The area of transition‐metal‐catalyzed direct arylation through cleavage of C H bonds has
undergone rapid development in recent years, and is becoming an increasingly viable …

Advances in imaging techniques now make it feasible to do things that were not previously
possible. Experiments in which interacting proteins are observed inside living cells are now …

Pyrrole is a heterocyclic ring template with multiple pharmacophores that provides a way for
the generation of library of enormous lead molecules. Owing to its vast pharmacological …

The transition-metal-catalyzed functionalization of C− H bonds is a powerful method for
generating carbon− carbon bonds. Although significant advances to this field have been …

The biaryl structural motif is a predominant feature in many pharmaceutically relevant and
biologically active compounds. As a result, for over a century1 organic chemists have sought …

During the last two decades there has been considerable growth in the development of
catalytic reactions capable of activating unreactive C–H bonds. These methods allow for the …

Dipyrromethene ligand scaffolds were synthesized bearing large aryl (2, 4, 6-Ph3C6H2,
abbreviated Ar) or alkyl (t Bu, adamantyl) flanking groups to afford three new disubstituted …

Terminal copper-nitrenoid complexes have inspired interest in their fundamental bonding
structures as well as their putative intermediacy in catalytic nitrene-transfer reactions. Here …

Conditions for the palladium-catalyzed direct arylation of a wide range of heterocycles with
aryl bromides are reported. Those conditions employ a stoichiometric ratio of both coupling …