Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

Cell death is an essential process in all living organisms and occurs through different
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …

Programmed cell death (PCD) enables cells to co-ordinate their exit to benefit the surviving
organism. A new study describes how cells can programme their death by inducing …

Various forms of cell death have been identified over the last decades with each relying on a
different subset of proteins for the activation and execution of their respective pathway (s). In …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function
stability and well-being. ECM detachment in localized tumors precedes abnormal …

Ruptured and intact plasma membranes are classically considered as hallmarks of necrotic
and apoptotic cell death, respectively. As such, apoptosis is usually considered a non …

Gasdermin E (GSDME) has an important role in inducing secondary necrosis/pyroptosis.
Upon apoptotic stimulation, it can be cleaved by activated caspase-3 to generate its N …

Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of
multivesicular bodies and the plasma membrane. They were shown to carry cell-specific …

In multicellular organisms, cell death is a critical and active process that maintains tissue
homeostasis and eliminates potentially harmful cells. There are three major types of …