Pathological impact of tau proteolytical process on neuronal and mitochondrial function: a crucial role in alzheimer's disease
MA Olesen, RA Quintanilla - Molecular Neurobiology, 2023 - Springer
Tau protein plays a pivotal role in the central nervous system (CNS), participating in
microtubule stability, axonal transport, and synaptic communication. Research interest has …
microtubule stability, axonal transport, and synaptic communication. Research interest has …
Amyloid Beta Oligomers Activate Death Receptors and Mitochondria-Mediated Apoptotic Pathways in Cerebral Vascular Smooth Muscle Cells; Protective Effects of …
Amyloid beta (Aβ) deposition within the brain vasculature is an early hallmark of Alzheimer's
disease (AD), which triggers loss of brain vascular smooth muscle cells (BVSMCs) in …
disease (AD), which triggers loss of brain vascular smooth muscle cells (BVSMCs) in …
Posttreatment with PaPE-1 Protects from Aβ-Induced Neurodegeneration Through Inhibiting the Expression of Alzheimer's Disease-Related Genes and Apoptosis …
BA Pietrzak-Wawrzyńska, A Wnuk… - Molecular …, 2024 - Springer
Targeting the non-nuclear estrogen receptor (ER) signaling has been postulated as novel
therapeutic strategy for central nervous system pathologies. Recently, we showed that newly …
therapeutic strategy for central nervous system pathologies. Recently, we showed that newly …
Role of activated p21-activated kinase 2 in methylmercury-induced embryotoxic effects on mouse blastocysts
CK Lee, FT Wang, CH Huang, WH Chan - Toxicology Research, 2023 - academic.oup.com
Methylmercury (MeHg), a biotransformation product derived from mercury or inorganic
mercury compounds in waterways, is a potent toxin that exerts hazardous effects on human …
mercury compounds in waterways, is a potent toxin that exerts hazardous effects on human …
Effects of TGF-β1 on Aβ-40 and α-β-γ Secretase Expression in Hippocampus and Prefrontal Cortex in Experimental Alzheimer's Disease
K Samet, S Polat, K Akillioglu, D Şaker… - Behavioural Brain …, 2025 - Elsevier
Alzheimer's disease is a chronic complex neurodegenerative disease characterized with
amyloid plaques and loss of neurons. TGF-β1 is important growth factor, plays critical roles …
amyloid plaques and loss of neurons. TGF-β1 is important growth factor, plays critical roles …
Serum Tau-A and Tau-C Levels and Their Association with Cognitive Impairment and Dementia Progression in a Memory Clinic Derived Cohort
TM Axelsen, P Høgh, AR Bihlet, MA Karsdal… - The Journal of …, 2024 - Springer
Background Serum-measured fragments of Tau cleaved by ADAM-10 (Tau-A) and Caspase-
3 (Tau-C) have been found linked to change in cognitive function and risk of dementia …
3 (Tau-C) have been found linked to change in cognitive function and risk of dementia …