The placenta is the gatekeeper between the mother and the fetus. Over the first trimester of
pregnancy, the fetus is nourished by uterine gland secretions in a process known as …

BACKGROUND With increasing significance of developmental programming effects
associated with placental dysfunction, more investigations are devoted to improving the …

The human placenta has a vital role in ensuring a successful pregnancy. Despite the
growing body of knowledge about its cellular compositions and functions, there has been …

Introduction Preeclampsia is a multisystemic, pregnancy-specific disorder united by new-
onset hypertension but with considerable variation in clinical manifestation, onset, and …

The placenta performs essential biologic functions for fetal development throughout
pregnancy. Placental dysfunction is at the root of multiple adverse birth outcomes such as …

Dyslipidemia in gestational diabetes has been associated with worse perinatal outcomes.
The ANGPTL3-4-8 axis regulates lipid metabolism, especially in the transition from fasting to …

Single-cell sequencing technologies enhance our understanding of cellular dynamics
throughout pregnancy. We outlined the workflow of single-cell sequencing techniques and …

Although recently developed placenta-on-chip systems opened promising perspectives for
placental barrier modeling, they still lack physiologically relevant trophoblasts and are …

The significance of the placenta in success pregnancy outcome has been generally
acknowledged. Despite our growing understanding of placenta cellular compositions and …

Single-cell RNA sequencing (scRNA-seq) is a method that focuses on the analysis of gene
expression profile in individual cells. This method has been successfully applied to answer …