Neurodegenerative disorders affect almost 30 million individuals leading to disability and
death. These disorders are characterized by pathological changes in disease-specific areas …

Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible
structure, particularly in the ferric form, such that it is able to sample a broad conformational …

Cell death and injury often lead to release or exposure of intracellular molecules called
damage-associated molecular patterns (DAMPs) or cell death-associated molecules. These …

Cell death is a fundamental ingredient of life. Thus, not surprisingly more than one form of
cell death exists. Several excellent reviews on various forms of cell death have already been …

Apoptosis is a highly regulated process of cell deletion and plays a fundamental role in the
maintenance of tissue homeostasis in the adult organism. Numerous studies in recent years …

The partial cross-utilization of molecules and pathways involved in opposing processes like
cell survival, proliferation and cell death, assures that mutations within one signaling …

Mitochondria are evolutionary endosymbionts derived from bacteria. Thus, they bear
molecules, such as mitochondrial DNA (mtDNA) that contains CpG DNA repeats and N …

Brevinin‐2R is a novel non‐hemolytic defensin that was isolated from the skin of the frog
Rana ridibunda. It exhibits preferential cytotoxicity towards malignant cells, including Jurkat …

Clinical studies have shown that HER-2/Neu is over-expressed in up to one-third of patients
with a variety of cancers, including B-cell acute lymphoblastic leukemia (B-ALL), breast …

This review is an attempt, for the first time, to describe advancements in sensing technology
for cytochrome c (cyt c) detection, at point-of-care (POC) application. Cyt c, a heme …