[HTML][HTML] Marine microbial L-asparaginase: biochemistry, molecular approaches and applications in tumor therapy and in food industry

FI Qeshmi, A Homaei, P Fernandes… - Microbiological Research, 2018 - Elsevier
The marine environment is a rich source of biological and chemical diversity. It covers more
than 70% of the Earth's surface and features a wide diversity of habitats, often displaying …

L-asparaginase–A promising biocatalyst for industrial and clinical applications

G Shakambari, B Ashokkumar… - Biocatalysis and …, 2019 - Elsevier
L-asparaginase is a versatile enzyme with application in food and therapeutics and under
constant quest for a reliable microbial source for commercial production. The review is an …

Biomimetic synthesis of silver nanoparticles using microalgal secretory carbohydrates as a novel anticancer and antimicrobial

A Ebrahiminezhad, M Bagheri… - Advances in Natural …, 2016 - iopscience.iop.org
Secreted carbohydrates by Chlorella vulgaris cells were used for reducing and capping
Silver nanoparticles (AgNPs). Oxygen-bearing functional groups on the carbohydrates found …

Efficient production of L-asparaginase from Bacillus licheniformis with low-glutaminase activity: optimization, scale up and acrylamide degradation studies

RV Mahajan, S Saran, K Kameswaran, V Kumar… - Bioresource …, 2012 - Elsevier
l-Asparaginase has potential as an anti-cancer drug and for prevention of acrylamide
formation in fried and baked foods. Production of the enzyme by Bacillus licheniformis (RAM …

l-Asparaginase Production by Moderate Halophilic Bacteria Isolated from Maharloo Salt Lake

A Ebrahiminezhad, S Rasoul-Amini… - Indian journal of …, 2011 - Springer
Abstract l-Asparaginase is an anti-neoplastic drug used in lymphoblastic leukemia
chemotherapy. Nowadays, this enzyme derived from bacterial sources, mostly l …

Production, purification and kinetic characterization of glutaminase free anti-leukemic L-asparaginase with low endotoxin level from novel soil isolate

P Prakash, HR Singh, SK Jha - Preparative Biochemistry & …, 2020 - Taylor & Francis
Anti-leukemic enzyme L-asparaginase despite having significant applicability in medicine,
holds side effects attributed to glutaminase activity and endotoxin content. Glutaminase …

Extracellular Production of Recombinant l-Asparaginase II in Escherichia coli: Medium Optimization Using Response Surface Methodology

MB Ghoshoon, A Berenjian, S Hemmati… - International Journal of …, 2015 - Springer
In this study a strategy based on using signal sequence and statistically optimized medium
was applied for efficient extracellular production of the recombinant form of the therapeutic …

Enzyme Engineering Strategies for the Bioenhancement of l-Asparaginase Used as a Biopharmaceutical

J Miranda, N Lefin, JF Beltran, LH Belén, A Tsipa… - BioDrugs, 2023 - Springer
Over the past few years, there has been a surge in the industrial production of recombinant
enzymes from microorganisms due to their catalytic characteristics being highly efficient …

Telomere-to-telomere genome assembly of asparaginase-producing Trichoderma simmonsii

D Chung, YM Kwon, Y Yang - BMC genomics, 2021 - Springer
Background Trichoderma is a genus of fungi in the family Hypocreaceae and includes
species known to produce enzymes with commercial use. They are largely found in soil and …

Oxytetracycline-induced inflammatory process without oxidative stress in blue mussels Mytilus trossulus

A Hallmann, D Leszczyńska, A Czumaj… - … Science and Pollution …, 2023 - Springer
Potentially harmful compounds including pharmaceuticals are commonly found in marine
waters and sediments. Amongst those, antibiotics and their metabolites are detected …