The efficacy and safety of first-line single-agent chemotherapy regimens in low-risk gestational trophoblastic neoplasia: a network meta-analysis

J Li, S Li, H Yu, J Wang, C Xu, X Lu - Gynecologic Oncology, 2018 - Elsevier
Objective There is no consensus regarding what should be the optimal single-agent
regimen in low-risk gestational trophoblastic neoplasia (LRGTN). we performed this network …

First-line monodrug chemotherapy in low-risk gestational trophoblastic neoplasia: a network meta-analysis

F Zhou, L Kemin - Frontiers in Oncology, 2024 - frontiersin.org
Objective The efficacy of the first-line monodrug chemotherapy has been generally
established for low-risk GTN. Most patients can achieve a complete response after the first …

Direct comparisons of efficacy and safety between actinomycin-D and methotrexate in women with low-risk gestational trophoblastic neoplasia: a meta-analysis of …

J Hao, W Zhou, M Zhang, H Yu, T Zhang, R An, Y Xue - BMC cancer, 2021 - Springer
Abstract Background Actinomycin-D (Act-D) and Methotrexate (MTX) are both effective first-
line agents for low-risk gestational trophoblastic neoplasia (LRGTN) with no consensus …

Pulse actinomycin D as first-line treatment of low-risk post-molar non-choriocarcinoma gestational trophoblastic neoplasia

L Li, X Wan, F Feng, T Ren, J Yang, J Zhao, F Jiang… - BMC cancer, 2018 - Springer
Background Little data exists predicting the resistance to actinomycin D (Act-D) single-agent
for gestational trophoblastic neoplasia (GTN). The objective was to determine the overall …

Predictive factors associated with resistance to initial methotrexate treatment in women with low‐risk gestational trophoblastic neoplasia

R Phianpiset, I Ruengkhachorn… - Asia‐Pacific Journal …, 2022 - Wiley Online Library
Aim To compare clinical characteristics and identify factors predictive of resistance to initial
treatment with methotrexate‐folinic acid (MTX‐FA) in women with low‐risk gestational …

放线菌素D 单日冲击疗法治疗低危妊娠滋养细胞肿瘤

范辰辰, 冯凤芝, 向阳, 万希润, 杨隽钧, 赵峻… - 协和医学杂志, 2017 - xhyxzz.pumch.cn
放线菌素D单日冲击疗法治疗低危妊娠滋养细胞肿瘤 邮件订阅 RSS 首页 关于本刊 1.期刊介绍
2.编委会 3.主编风采 投稿指南 1.投稿须知 2.版权转让协议 3.研究报告规范清单 出版声明 1.出版 …

[HTML][HTML] Resistance to single-agent chemotherapy in low-risk gestational trophoblastic neoplasia

S Sheikhhasani, A Abdolrazaghnejad… - Caspian Journal of …, 2023 - ncbi.nlm.nih.gov
Background: Methotrexate (MTX) and actinomycin D (ActD) have been used as first-line
chemotherapy agents in the treatment of low-risk gestational trophoblastic neoplasia (GTN) …

Placentomegaly in Partial Mole: Current Perspectives on Diagnosis, Complications, and Therapeutic Approaches-A Comprehensive Review

A Patel, A Jaiswal, D Dewani, N Sethi… - Multidisciplinary …, 2025 - malque.pub
Placentomegaly, or abnormal enlargement of the placenta, is a common feature in partial
molar pregnancies, a subtype of gestational trophoblastic disease (GTD) characterized by …

低危型妊娠滋养细胞肿瘤耐药, 复发相关因素的研究进展.

陈金娟, 易晓芳 - Journal of International Obstetrics & …, 2016 - search.ebscohost.com
低危型妊娠滋养细胞肿瘤的治愈率几乎100%, 但仍有10% 耀67% 的患者对初始化疗耐药, 1.3%
耀8.3% 的患者初始化疗后复发, 而发生耐药, 复发的患者不仅面临着经济上的负担 …

3-磷酸甘油酸脱氢酶在肿瘤中的研究进展.

张晶, 张淑兰 - Journal of International Obstetrics & …, 2016 - search.ebscohost.com
3-磷酸甘油酸脱氢酶(3-PGDH 或PHGDH) 是丝氨酸合成途径的关键酶. 其编码基因PHGDH
位于人类染色体1p12, 在一些正常组织中存在高表达, 特别对神经系统功能发育有着重要作用 …