Inhibitors of acetylcholinesterase and butyrylcholinesterase meet immunity

M Pohanka - International journal of molecular sciences, 2014 - mdpi.com
Acetylcholinesterase (AChE) inhibitors are widely used for the symptomatic treatment of
Alzheimer's disease and other dementias. More recent use is for myasthenia gravis. Many of …

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis

M Srinivasan, DK Lahiri - Expert opinion on therapeutic targets, 2015 - Taylor & Francis
Introduction: Advances in molecular pathogenesis suggest that the chronic inflammation is a
shared mechanism in the initiation and progression of multiple neurodegenerative diseases …

Effects of dietary ginkgo biloba leaf extract on growth performance, plasma biochemical parameters, fish composition, immune responses, liver histology, and immune …

X Tan, Z Sun, Q Liu, H Ye, C Zou, C Ye, A Wang… - Fish & shellfish …, 2018 - Elsevier
For thousands of years, leaves from the Ginkgo biloba tree have been a common treatment
in Chinese medicine. The present study was conducted to investigate the effects of dietary …

Association between periodontal health status and cognitive Abilitie s. The role of cytokine profile and systemic inflammation

M Sochocka, M SobczyŦ# 132; ski… - Current Alzheimer …, 2017 - benthamdirect.com
Background: Contemporary neurobiology, periodontal medicine, and immunology are now
focusing on the relationship between chronic periodontitis and systemic diseases, which …

The potential of Ginkgo biloba in the treatment of human diseases and the relationship to Nrf2–mediated antioxidant protection

Y Li, X Zhu, K Wang, L Zhu, M Murray… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives This review summarises the current findings regarding the therapeutic effects of
GBE and its active ingredients in relation to the Nrf2 antioxidant cascade, to provide …

[HTML][HTML] Effects of feeding fermented Ginkgo biloba leaves on small intestinal morphology, absorption, and immunomodulation of early lipopolysaccharide-challenged …

X Zhang, L Zhao, F Cao, H Ahmad, G Wang, T Wang - Poultry Science, 2013 - Elsevier
Aspergillus niger-fermented-Ginkgo biloba leaves (FG) and the comparative effect with
nonfermented (NF)-Ginkgo leaves were investigated on morphology, absorption, and …

Host-directed antimicrobial drugs with broad-spectrum efficacy against intracellular bacterial pathogens

DM Czyż, LP Potluri, N Jain-Gupta, SP Riley… - MBio, 2014 - Am Soc Microbiol
We sought a new approach to treating infections by intracellular bacteria, namely, by altering
host cell functions that support their growth. We screened a library of 640 Food and Drug …

Ginkgo biloba leaves extract (EGb 761) attenuates lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and NF-κB-dependent matrix …

CH Huang, ML Yang, CH Tsai, YC Li, YJ Lin, YH Kuan - Phytomedicine, 2013 - Elsevier
Acute lung injury (ALI) presents high mortality and morbidity clinically and by far no effective
preventive strategy has been established. Extract of Ginkgo biloba leaves, EGb 761, is a …

Dietary Ginkgo biloba leaf extract alters immune-related gene expression and disease resistance to Aeromonas hydrophila in common carp Cyprinus carpio

L Bao, Y Chen, H Li, J Zhang, P Wu, KE Ye, H Ai… - Fish & shellfish …, 2019 - Elsevier
Ginkgo biloba leaf is widely used in traditional medicine in China. The present study aimed
to illustrate the effects of dietary Ginkgo biloba leaf extract (GBLE) on growth performance …

Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades …

EM Elbaz, RM Essam, KA Ahmed, MH Safwat - International …, 2023 - Elsevier
Ulcerative colitis (UC) is a persistent inflammatory bowel disease (IBD) that is regarded as a
risk factor for cognitive impairment. Donepezil (DON), a centrally acting acetylcholinesterase …