Research progress of safety of zearalenone: A review

X Han, B Huangfu, T Xu, W Xu, C Asakiya, K Huang… - Toxins, 2022 - mdpi.com
Zearalenone, a mycotoxin produced by fungi of the genus Fusarium, widely exists in animal
feed and human food. The structure of zearalenone is similar to estrogen, so it mainly has …

Hippo signaling in the ovary: emerging roles in development, fertility, and disease

KL Clark, JW George, E Przygrodzka… - Endocrine …, 2022 - academic.oup.com
Emerging studies indicate that the Hippo pathway, a highly conserved pathway that
regulates organ size control, plays an important role in governing ovarian physiology …

[HTML][HTML] Causes of low milk supply: the roles of estrogens, progesterone, and related external factors

X Jin, SL Perrella, CT Lai, NL Taylor, DT Geddes - Advances in Nutrition, 2024 - Elsevier
Low milk supply (LMS) poses a significant challenge to exclusive and continued
breastfeeding, affecting∼ 10% to 15% of mothers. Milk production is intricately regulated by …

The importance of transcriptomics and proteomics for studying molecular mechanisms of mycotoxin exposure: A review

A Cimbalo, M Frangiamone, G Font… - Food and Chemical …, 2022 - Elsevier
This review aims to highlight recent advances where transcriptomics and proteomics have
been used as a key tool to understand molecular toxicity of mycotoxins. The most studied …

Oxidative stress as a plausible mechanism for zearalenone to induce genome toxicity

YQ Feng, AH Zhao, JJ Wang, Y Tian, ZH Yan, M Dri… - Gene, 2022 - Elsevier
Zearalenone (ZEN), a common non-steroidal estrogenic mycotoxin of the Fusarium genus, is
one of the most frequent and powerful contaminant of grains and cereal products …

Altered histone abundance as a mode of ovotoxicity during 7, 12-dimethylbenz [a] anthracene exposure with additive influence of obesity

JK Rishi, K Timme, HE White, KC Kerns… - Biology of …, 2024 - academic.oup.com
Histones are slowly evolving chromatin components and chromatin remodeling can
incorporate histone variants differing from canonical histones as an epigenetic modification …

PFOA-induced ovotoxicity differs between lean and obese mice with impacts on ovarian reproductive and DNA damage sensing and repair proteins

M Estefanía González-Alvarez, A Severin… - Toxicological …, 2022 - academic.oup.com
Perfluorooctanoic acid (PFOA) is an environmentally persistent perfluoroalkyl substance that
is widely used in consumer products. Exposure to PFOA is associated with reproductive and …

Phenotypic, endocrinological, and metabolic effects of zearalenone exposure and additive effect of heat stress in prepubertal female pigs

CM Roach, EJ Mayorga, LH Baumgard, JW Ross… - Journal of Thermal …, 2024 - Elsevier
Independently, both heat stress (HS) and zearalenone (ZEN) compromise female
reproduction, thus the hypothesis that ZEN would affect phenotypic, endocrine, and …

Obesity partially potentiates dimethylbenz [a] anthracene-exposed ovotoxicity by altering the DNA damage repair response in mice

JK Rishi, K Timme, HE White, KC Kerns… - Biology of …, 2023 - academic.oup.com
Obesity adversely affects reproduction, impairing oocyte quality, fecundity, conception, and
implantation. The ovotoxicant, dimethylbenz [a] anthracene, is biotransformed into a …

Applications of mycotoxin biomarkers in human biomonitoring for exposome-health studies: Past, present, and future

IO Owolabi, K Siwarak, B Greer, A Rajkovic… - Exposure and …, 2024 - Springer
This publication reviews the state-of-the-art human biological monitoring (HBM) of mycotoxin
biomarkers in breast milk, plasma, serum, and whole blood samples with a focus on the past …