The influenza A virus RNA genome segments are packaged in ribonucleoprotein complexes
containing RNA polymerase and nucleoprotein. The ribonucleoprotein is involved in the …

The influenza A viruses are the causative agents of respiratory disease that occurs as yearly
epidemics and occasional pandemics. These viruses are endemic in wild avian species and …

Mx1 is a GTPase that is part of the antiviral response induced by type I and type III
interferons in the infected host. It inhibits influenza virus infection by blocking viral …

Genetically encoded biosensors allow the noninvasive imaging of specific biochemical or
biorecognition processes with the preservation of subcellular spatial and temporal …

Influenza viruses are major human pathogens responsible for respiratory diseases affecting
millions of people worldwide and characterized by high morbidity and significant mortality …

Over the past 2 decades, several novel influenza virus proteins have been identified that
modulate viral infections in vitro and/or in vivo. The PB2 segment, which is one of the longest …

The emergence of new pandemic influenza A viruses requires overcoming barriers to cross-
species transmission as viruses move from animal reservoirs into humans. This complicated …

Two viruses isolated during the highly pathogenic avian influenza (HPAI) H7N7 virus
outbreak in The Netherlands in 2003, one isolated from a person with conjunctivitis and one …

Viral DNA and RNA polymerases are two kinds of very important enzymes that synthesize
the genetic materials of the virus itself, and they have become extremely favorable targets for …

During influenza A virus (IAV) infections, viral proteins are targeted by cellular E3 ligases for
modification with ubiquitin. Here, we decipher and functionally explore the ubiquitination …