Regulation of cerebral blood flow and metabolism during exercise

KJ Smith, PN Ainslie - Experimental physiology, 2017 - Wiley Online Library
New Findings What is the topic of this review? The manuscript collectively combines the
experimental observations from> 100 publications focusing on the regulation of cerebral …

Physiology, pathophysiology and (mal) adaptations to chronic apnoeic training: a state-of-the-art review

A Elia, M Gennser, PS Harlow, MJ Lees - European journal of applied …, 2021 - Springer
Breath-hold diving is an activity that humans have engaged in since antiquity to forage for
resources, provide sustenance and to support military campaigns. In modern times, breath …

Physiology of static breath holding in elite apneists

AR Bain, I Drvis, Z Dujic, DB MacLeod… - Experimental …, 2018 - Wiley Online Library
New Findings What is the topic of this review? This review provides an up‐to‐date
assessment of the physiology involved with extreme static dry‐land breath holding in trained …

Carbon dioxide changes during high-flow nasal oxygenation in apneic patients: a single-center randomized controlled noninferiority trial

T Riva, R Greif, H Kaiser, T Riedel, M Huber… - …, 2021 - ingentaconnect.com
Background: Anesthesia studies using high-flow, humidified, heated oxygen delivered via
nasal cannulas at flow rates of more than 50 l· min–1 postulated a ventilatory effect because …

Hypoxemia increases blood-brain barrier permeability during extreme apnea in humans

DM Bailey, AR Bain, RL Hoiland… - Journal of Cerebral …, 2022 - journals.sagepub.com
Voluntary asphyxia imposed by static apnea challenges blood-brain barrier (BBB) integrity
in humans through transient extremes of hypertension, hypoxemia and hypercapnia. In the …

Breath-hold diving–the physiology of diving deep and returning

A Patrician, Ž Dujić, B Spajić, I Drviš… - Frontiers in …, 2021 - frontiersin.org
Breath-hold diving involves highly integrative physiology and extreme responses to both
exercise and asphyxia during progressive elevations in hydrostatic pressure. With …

Surviving without oxygen: how low can the human brain go?

DM Bailey, CK Willie, RL Hoiland, AR Bain… - … altitude medicine & …, 2017 - liebertpub.com
Abstract Bailey, Damian M., Christopher K. Willie, Ryan L. Hoiland, Anthony R. Bain, David
B. MacLeod, Maria A. Santoro, Daniel K. DeMasi, Andrea Andrijanic, Tanja Mijacika, Otto F …

Severe hypoxaemic hypercapnia compounds cerebral oxidative–nitrosative stress during extreme apnoea: Implications for cerebral bioenergetic function

DM Bailey, AR Bain, RL Hoiland… - The Journal of …, 2024 - Wiley Online Library
We examined the extent to which apnoea‐induced extremes of oxygen demand/carbon
dioxide production impact redox regulation of cerebral bioenergetic function. Ten ultra‐elite …

Hypercapnia is essential to reduce the cerebral oxidative metabolism during extreme apnea in humans

AR Bain, PN Ainslie, OF Barak… - Journal of Cerebral …, 2017 - journals.sagepub.com
The cerebral metabolic rate of oxygen (CMRO2) is reduced during apnea that yields
profound hypoxia and hypercapnia. In this study, to dissociate the impact of hypoxia and …

Effects of apnoea training on aerobic and anaerobic performance: A systematic review and meta-analysis

F de Asís-Fernández, D Sereno, AP Turner… - Frontiers in …, 2022 - frontiersin.org
Background Trained breath-hold divers have shown physiological adaptations that might
improve athletes' aerobic and anaerobic performance. Objective This study aimed to …