Evidence for and against direct kidney infection by SARS-CoV-2 in patients with COVID-19
Despite evidence of multiorgan tropism of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in patients with coronavirus disease 2019 (COVID-19), direct viral kidney …
(SARS-CoV-2) in patients with coronavirus disease 2019 (COVID-19), direct viral kidney …
[HTML][HTML] ACE2 down-regulation may act as a transient molecular disease causing RAAS dysregulation and tissue damage in the microcirculatory environment among …
SG Ramos, BA da Cruz Rattis, G Ottaviani… - The American journal of …, 2021 - Elsevier
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the etiological
agent of COVID-19 (coronavirus disease 2019) and the cause of the current pandemic …
agent of COVID-19 (coronavirus disease 2019) and the cause of the current pandemic …
Expression of ACE2, soluble ACE2, angiotensin I, angiotensin II and angiotensin-(1-7) is modulated in COVID-19 patients
The etiological agent of COVID-19 SARS-CoV-2, is primarily a pulmonary-tropic
coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the …
coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the …
Efficacy of losartan in hospitalized patients with COVID-19–induced lung injury: a randomized clinical trial
MA Puskarich, NE Ingraham, LH Merck… - JAMA network …, 2022 - jamanetwork.com
Importance SARS-CoV-2 viral entry may disrupt angiotensin II (AII) homeostasis,
contributing to COVID-19 induced lung injury. AII type 1 receptor blockade mitigates lung …
contributing to COVID-19 induced lung injury. AII type 1 receptor blockade mitigates lung …
Concerns on the specificity of commercial ELISAs for the measurement of angiotensin (1–7) and angiotensin II in human plasma
MC Chappell, NT Pirro, AM South, TYM Gwathmey - Hypertension, 2021 - Am Heart Assoc
Ang II were thawed on ice and pooled for comparison of peptide values between the ELISA
and radioimmunoassay methods. Blood samples were collected directly into EDTA …
and radioimmunoassay methods. Blood samples were collected directly into EDTA …
Appraising the preclinical evidence of the role of the renin-angiotensin-Aldosterone system in antenatal programming of maternal and offspring cardiovascular health …
There is increasing interest in the long-term cardiovascular health of women with
complicated pregnancies and their affected offspring. Emerging antenatal risk factors such …
complicated pregnancies and their affected offspring. Emerging antenatal risk factors such …
A pilot study to assess the circulating renin-angiotensin system in COVID-19 acute respiratory failure
DC Files, KW Gibbs, CL Schaich… - … of Physiology-Lung …, 2021 - journals.physiology.org
The renin-angiotensin system (RAS) is fundamental to COVID-19 pathobiology, due to the
interaction between the SARS-CoV-2 virus and the angiotensin-converting enzyme 2 …
interaction between the SARS-CoV-2 virus and the angiotensin-converting enzyme 2 …
Evaluating sources of bias in observational studies of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker use during COVID-19: beyond …
Concerns over ACE inhibitor or ARB use to treat hypertension during COVID-19 remain
unresolved. Although studies using more robust methodologies provided some clarity …
unresolved. Although studies using more robust methodologies provided some clarity …
Highly efficient SARS-CoV-2 infection of human cardiomyocytes: spike protein-mediated cell fusion and its inhibition
CK Navaratnarajah, DR Pease, PJ Halfmann… - Journal of …, 2021 - Am Soc Microbiol
Severe cardiovascular complications can occur in coronavirus disease of 2019 (COVID-19)
patients. Cardiac damage is attributed mostly to the aberrant host response to acute …
patients. Cardiac damage is attributed mostly to the aberrant host response to acute …
The molecular mechanism of multiple organ dysfunction and targeted intervention of COVID-19 based on time-order transcriptomic analysis
M Zou, X Su, L Wang, X Yi, Y Qiu, X Yin… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) pandemic is caused by the novel coronavirus that
has spread rapidly around the world, leading to high mortality because of multiple organ …
has spread rapidly around the world, leading to high mortality because of multiple organ …