Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition
F Wang, CB Marshall, M Ikura - Cellular and Molecular Life Sciences, 2013 - Springer
In eukaryotic cells, gene transcription is regulated by sequence-specific DNA-binding
transcription factors that recognize promoter and enhancer elements near the transcriptional …
transcription factors that recognize promoter and enhancer elements near the transcriptional …
Coordinated dialogue between UHRF1 and DNMT1 to ensure faithful inheritance of methylated DNA patterns
DNA methylation, catalyzed by DNA methyltransferases (DNMTs), is an epigenetic mark that
needs to be faithfully replicated during mitosis in order to maintain cell phenotype during …
needs to be faithfully replicated during mitosis in order to maintain cell phenotype during …
Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism
IO Torres, KM Kuchenbecker, CI Nnadi… - Nature …, 2015 - nature.com
The retinoblastoma binding protein KDM5A removes methyl marks from lysine 4 of histone
H3 (H3K4). Misregulation of KDM5A contributes to the pathogenesis of lung and gastric …
H3 (H3K4). Misregulation of KDM5A contributes to the pathogenesis of lung and gastric …
Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate
KA Gelato, M Tauber, MS Ong, S Winter… - Molecular cell, 2014 - cell.com
UHRF1 is a multidomain protein crucially linking histone H3 modification states and DNA
methylation. While the interaction properties of its specific domains are well characterized …
methylation. While the interaction properties of its specific domains are well characterized …
Increasing role of UHRF1 in the reading and inheritance of the epigenetic code as well as in tumorogenesis
Epigenetic mechanisms such as DNA methylation and histone posttranslational
modifications, allow cells to maintain the phenotype throughout successive mitosis. UHRF1 …
modifications, allow cells to maintain the phenotype throughout successive mitosis. UHRF1 …
Histone acetyltransferases in rice (Oryza sativaL.): phylogenetic analysis, subcellular localization and expression
X Liu, M Luo, W Zhang, J Zhao, J Zhang, K Wu, L Tian… - BMC plant biology, 2012 - Springer
Abstract Background Histone acetyltransferases (HATs) play an important role in eukaryotic
transcription. Eight HATs identified in rice (OsHATs) can be organized into four families …
transcription. Eight HATs identified in rice (OsHATs) can be organized into four families …
[HTML][HTML] Expression analysis of histone acetyltransferases in rice under drought stress
H Fang, X Liu, G Thorn, J Duan, L Tian - Biochemical and Biophysical …, 2014 - Elsevier
Histone acetylation is one of the vital reversible modifications of chromatin structure that
regulates gene expression in eukaryotes. Histone acetyltransferases (HATs) and histone …
regulates gene expression in eukaryotes. Histone acetyltransferases (HATs) and histone …
An allosteric interaction links USP7 to deubiquitination and chromatin targeting of UHRF1
The protein stability and chromatin functions of UHRF1 (ubiquitin-like, containing PHD and
RING finger domains, 1) are regulated in a cell-cycle-dependent manner. We report a …
RING finger domains, 1) are regulated in a cell-cycle-dependent manner. We report a …
The arginine methyltransferase PRMT6 regulates DNA methylation and contributes to global DNA hypomethylation in cancer
DNA methylation plays crucial roles in chromatin structure and gene expression. Aberrant
DNA methylation patterns, including global hypomethylation and regional hypermethylation …
DNA methylation patterns, including global hypomethylation and regional hypermethylation …
Cross-talk among epigenetic modifications: lessons from histone arginine methylation
D Molina-Serrano, V Schiza… - Biochemical Society …, 2013 - portlandpress.com
Epigenetic modifications, including those occurring on DNA and on histone proteins, control
gene expression by establishing and maintaining different chromatin states. In recent years …
gene expression by establishing and maintaining different chromatin states. In recent years …