Mast cells and basophils are key contributors to allergies and other inflammatory diseases
since they are the most prominent source of histamine as well as numerous additional …

Mast cells (MCs) act as primary effectors in inflammatory and allergic reactions by releasing
intracellularly-stored inflammatory mediators in diseases. The two major pathways for MC …

Mast cells (MCs) are important sensor and effector cells of the immune system that are
involved in many physiological and pathological conditions. Increasing evidence suggests …

Mast cells are localized throughout the body and mediate allergic, immune, and
inflammatory reactions. They are heterogeneous, tissue-resident, long-lived, and granulated …

Rheumatic and joint diseases, as exemplified by osteoarthritis and rheumatoid arthritis, are
among the most widespread painful and disabling pathologies across the globe. Given the …

Inflammation, an essential tissue response to extrinsic/intrinsic damage, is a very dynamic
process in terms of complexity and extension of cellular and metabolic involvement. The aim …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that causes chronic
inflammation of the joints. RA is a heterogeneous disorder caused by an abnormal …

Objectives Mast cells (MCs) are involved in the pathogenesis of rheumatoid arthritis (RA).
However, their contribution remains controversial. To establish their role in RA, we analysed …

Mast cells are potent actors involved in inflammatory reactions in various tissues, including
both in the intimal and the adventitial layers of atherosclerotic arteries. In the arterial intima …

Mast cells play pivotal roles in innate and adaptive immunities but are also culprits in allergy,
autoimmunity, and cardiovascular diseases. Mast cells respond to environmental changes …