Enzymes are very efficient catalysts that are essential for the functioning of living organisms.
The low efficiency of biocatalysts produced de novo relative to those that have evolved …

Many enzymes contain tunnels and gates that are essential to their function. Gates
reversibly switch between open and closed conformations and thereby control the traffic of …

Neonates at risk of childhood atopy and asthma exhibit perturbation of the gut microbiome,
metabolic dysfunction and increased concentrations of 12, 13-diHOME in their faeces …

The treatment of tuberculosis is becoming more difficult due to the ever increasing
prevalence of drug resistance. Thus, it is imperative that novel anti-tuberculosis agents, with …

Although there has been limited application in the field to date, human milk omics research
continues to gain traction. Human milk lipidomics and metabolomics research is particularly …

Out of the prominent global ailments, tuberculosis (TB) is still one of the leading causes of
death worldwide due to infectious disease. Development of new drugs that shorten the …

Optically pure epoxides are essential chiral precursors for the production of (S)-
propranolol,(S)-alprenolol, and other β-adrenergic receptor blocking drugs. Although the …

The hydrolytic ring opening of epoxides is an important biosynthetic transformation and is
also applied industrially. We report the first organocatalytic variant of this reaction, exploiting …

Epoxide hydrolases (EH), enzymes present in all living organisms, transform epoxide-
containing lipids to 1, 2-diols by the addition of a molecule of water. Many of these …

Magnetic nanoparticles due to their unique properties have emerged as an excellent
support for the immobilization/stabilization of enzymes. Various kinds of required …