A practical approach to the diagnosis and management of classic lichen planopilaris

K Svigos, L Yin, L Fried, K Lo Sicco… - American Journal of …, 2021 - Springer
Lichen planopilaris is a primary lymphocytic cicatricial alopecia that commonly presents with
hair loss at the vertex or parietal scalp. Patients may also have associated scalp itching …

A systematic review and Bayesian network meta-analysis of medical therapies for lichen planopilaris

H Husein-ElAhmed, S Husein-ElAhmed - Dermatology, 2024 - karger.com
Background: Lichen planopilaris (LPP) is a primary chronic lymphocytic cutaneous disorder
that selectively destroys the hair follicles, resulting in scarring alopecia. Unfortunately …

Methotrexate for inflammatory skin disease in pediatric patients: Consensus treatment guidelines

EC Siegfried, LM Arkin, YE Chiu, AA Hebert… - Pediatric …, 2023 - Wiley Online Library
Methotrexate (MTX) is a readily accessible drug, first used in 1948 and employed for a wide
variety of indications since then. However, despite widespread off‐label use, FDA labeling …

What can we learn from treatments of oral lichen planus?

T Wu, Y Bai, Y Jing, F Chen - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
Oral lichen planus (OLP), a T-lymphocyte-mediated disease of the oral mucosa, has a
complex pathogenesis that involves a number of factors. The disease is characterized by …

Comparative efficacy study combination of oral methotrexate and prednisolone versus oral methotrexate in patients with lichen planopilaris

F Fatemi, F Esfahanian, A Asilian… - Dermatology …, 2022 - Wiley Online Library
Background. Lichen planopilaris (LPP) is a rare inflammatory disorder of the scalp that
causes cicatricial alopecia. No therapeutic approach has been approved for this disease …

Treatment modalities for lymphocytic and neutrophilic scarring alopecia

O Ezemma, S Devjani, KJ Kelley, MM Senna - Journal of the American …, 2023 - Elsevier
Primary cicatricial alopecia can result in permanent hair loss from the destruction of hair
follicles. Early intervention is key in controlling disease progression, reducing symptoms …

Efficacy and safety of oral pioglitazone in the management of lichen planopilaris in comparison with clobetasol: A randomized clinical trial

V Lajevardi, M Ghiasi, K Balighi… - Dermatologic …, 2022 - Wiley Online Library
Lichen planopilaris (LPP) is a scarring alopecia for which no treatment with remarkable
effect has been identified. Pioglitazone has been reported as a possible therapeutic option …

[HTML][HTML] Frontiers in lichen planopilaris and frontal fibrosing alopecia research: pathobiology progress and translational horizons

MM Senna, E Peterson, I Jozic, J Chéret, R Paus - JID innovations, 2022 - Elsevier
Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) are primary, lymphocytic
cicatricial hair loss disorders. These model epithelial stem cell (SC) diseases are thought to …

Exploring Remission Dynamics and Prognostic Factors in Lichen Planopilaris: A Retrospective Cohort Study

A Lyakhovitsky, T Zilbermintz, Z Segal, E Galili… - Dermatology, 2024 - karger.com
Introduction: Lichen planopilaris (LPP) is a common type of primary cicatricial alopecia.
Previous studies focused on the epidemiology, clinical characteristics, and treatment of LPP …

Clinical Effectiveness of Two Old Immunosuppressant Drugs, Methotrexate and Azathioprine, in the Treatment of Lichen Planopilaris: A Randomized Clinical Trial

M Saber, P Hajheidari, F Fatemi Naeini… - Dermatologic …, 2024 - Wiley Online Library
Background. Lichen planopilaris is the leading cause of cicatricial alopecia, and its
management is challenging for dermatologists. It is a cell‐mediated autoimmune disorder in …