The fight against cancer by microgravity: the multicellular spheroid as a metastasis model
Cancer is a disease exhibiting uncontrollable cell growth and spreading to other parts of the
organism. It is a heavy, worldwide burden for mankind with high morbidity and mortality …
organism. It is a heavy, worldwide burden for mankind with high morbidity and mortality …
Ocular conditions and injuries, detection and management in spaceflight
E Meer, S Grob, EL Antonsen, A Sawyer - npj Microgravity, 2023 - nature.com
Ocular trauma or other ocular conditions can be significantly debilitating in space. A
literature review of over 100 articles and NASA evidence books, queried for eye related …
literature review of over 100 articles and NASA evidence books, queried for eye related …
Physiological alterations in relation to space flight: the role of nutrition
S Chaloulakou, KA Poulia, D Karayiannis - Nutrients, 2022 - mdpi.com
Astronauts exhibit several pathophysiological changes due to a variety of stressors related
to the space environment, including microgravity, space radiation, isolation, and …
to the space environment, including microgravity, space radiation, isolation, and …
Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice
Spaceflight-related stresses impact health via various body systems, including the
haematopoietic and immune systems, with effects ranging from moderate alterations of …
haematopoietic and immune systems, with effects ranging from moderate alterations of …
Pathophysiology, risk, diagnosis, and management of venous thrombosis in space: where are we now?
The recent incidental discovery of an asymptomatic venous thrombosis (VT) in the internal
jugular vein of an astronaut on the International Space Station prompted a necessary …
jugular vein of an astronaut on the International Space Station prompted a necessary …
Cardiovascular, lymphatic, and ocular health in space
V Ly, SR Velichala, AR Hargens - Life, 2022 - mdpi.com
Life on Earth has evolved continuously under Earth's 1 G force and the protection of the
magnetosphere. Thus, astronauts exhibit maladaptive physiological responses during space …
magnetosphere. Thus, astronauts exhibit maladaptive physiological responses during space …
Effects of simulated microgravity in vitro on human metaphase II oocytes: an electron microscopy-based study
S Miglietta, L Cristiano, MSB Espinola, MG Masiello… - Cells, 2023 - mdpi.com
Highlights What are the main findings? For the first time, the in vitro effects of simulated
microgravity using a Random Positioning Machine on the ultrastructural features of human …
microgravity using a Random Positioning Machine on the ultrastructural features of human …
Going against the flow: are venous thromboembolism and impaired cerebral drainage critical risks for spaceflight?
After more than 50 years of human spaceflight with a perpetual focus on altered blood flow
in microgravity, the recent and unforeseen in-flight internal jugular venous thrombosis (VT) …
in microgravity, the recent and unforeseen in-flight internal jugular venous thrombosis (VT) …
Search for venous endothelial biomarkers heralding venous thromboembolism in space: a qualitative systematic review of terrestrial studies
Background: The recent discovery of a venous thrombosis in the internal jugular vein of an
astronaut has highlighted the need to predict the risk of venous thromboembolism in …
astronaut has highlighted the need to predict the risk of venous thromboembolism in …
Ionizing radiation, cerebrovascular disease, and consequent dementia: A review and proposed framework relevant to space radiation exposure
Space exploration requires the characterization and management or mitigation of a variety
of human health risks. Exposure to space radiation is one of the main health concerns …
of human health risks. Exposure to space radiation is one of the main health concerns …