Characteristics, prevention, and management of cardiovascular disease in people living with HIV: a scientific statement from the American Heart Association

MJ Feinstein, PY Hsue, LA Benjamin, GS Bloomfield… - Circulation, 2019 - Am Heart Assoc
As early and effective antiretroviral therapy has become more widespread, HIV has
transitioned from a progressive, fatal disease to a chronic, manageable disease marked by …

Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART

S Zicari, L Sessa, N Cotugno, A Ruggiero, E Morrocchi… - Viruses, 2019 - mdpi.com
Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …

Platelet and endothelial activation as potential mechanisms behind the thrombotic complications of COVID-19 patients

P Canzano, M Brambilla, B Porro, N Cosentino… - Basic to Translational …, 2021 - jacc.org
The authors hypothesized that the cytokine storm described in COVID-19 patients may lead
to consistent cell-based tissue factor (TF)-mediated activation of coagulation, procoagulant …

A neutralizing monoclonal antibody for hospitalized patients with Covid-19

Activ-3/Tico Ly-CoV555 Study … - New England Journal of …, 2021 - Mass Medical Soc
Background LY-CoV555, a neutralizing monoclonal antibody, has been associated with a
decrease in viral load and the frequency of hospitalizations or emergency department visits …

A test in context: D-dimer

JI Weitz, JC Fredenburgh, JW Eikelboom - Journal of the American College …, 2017 - jacc.org
D-dimer is a soluble fibrin degradation product that results from ordered breakdown of
thrombi by the fibrinolytic system. Numerous studies have shown that D-dimer serves as a …

Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy: Challenges of immunological non-responders

X Yang, B Su, X Zhang, Y Liu, H Wu… - Journal of leukocyte …, 2020 - academic.oup.com
The morbidity and mortality of HIV type-1 (HIV-1)-related diseases were dramatically
diminished by the grounds of the introduction of potent antiretroviral therapy, which induces …

Trends in underlying causes of death in people with HIV from 1999 to 2011 (D: A: D): a multicohort collaboration

CJ Smith, L Ryom, R Weber, P Morlat, C Pradier… - The Lancet, 2014 - thelancet.com
Background With the advent of effective antiretroviral treatment, the life expectancy for
people with HIV is now approaching that seen in the general population. Consequently, the …

The end of AIDS: HIV infection as a chronic disease

SG Deeks, SR Lewin, DV Havlir - The lancet, 2013 - thelancet.com
The success of antiretroviral therapy has led some people to now ask whether the end of
AIDS is possible. For patients who are motivated to take therapy and who have access to …

HIV infection: epidemiology, pathogenesis, treatment, and prevention

G Maartens, C Celum, SR Lewin - The Lancet, 2014 - thelancet.com
HIV prevalence is increasing worldwide because people on antiretroviral therapy are living
longer, although new infections decreased from 3· 3 million in 2002, to 2· 3 million in 2012 …

[HTML][HTML] National Lipid Association recommendations for patient-centered management of dyslipidemia: part 2

TA Jacobson, KC Maki, CE Orringer, PH Jones… - Journal of clinical …, 2015 - Elsevier
Abstract An Expert Panel convened by the National Lipid Association previously developed
a consensus set of recommendations for the patient-centered management of dyslipidemia …