Bicyclic boronate β‐lactamase inhibitors: the present hope against deadly bacterial pathogens

E Lence, C González‐Bello - Advanced Therapeutics, 2021 - Wiley Online Library
The use of β‐lactamase inhibitors in combination with β‐lactam antibiotics is an emerging
area in drug discovery. This strategy allows the restoration of the therapeutic efficacy of …

Nationwide surveillance in Thailand revealed genotype-dependent dissemination of carbapenem-resistant Enterobacterales

D Takeuchi, A Kerdsin, Y Akeda… - Microbial …, 2022 - microbiologyresearch.org
Carbapenem-resistant Enterobacterales (CRE) are a serious public health threat because of
their rapid dissemination. To determine the epidemiological and genetic characteristics of …

Regional Spread of blaNDM-1-Containing Klebsiella pneumoniae ST147 in Post-Acute Care Facilities

Z Lapp, R Crawford, A Miles-Jay, A Pirani… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Carbapenem-resistant Enterobacterales (CRE) harboring blaKPC
have been endemic in Chicago-area healthcare networks for more than a decade. During …

Coinfections of two strains of NDM-1-and OXA-232-coproducing Klebsiella pneumoniae in a kidney transplant patient

DA Contreras, SP Fitzwater… - Antimicrobial agents …, 2020 - Am Soc Microbiol
We report here a fatal case of carbapenem-resistant Klebsiella pneumoniae (CRKP)
infections in a renal transplant patient without a travel history in the prior year, from whom 2 …

Clonal dissemination of OXA-232 carbapenemase-producing Klebsiella pneumoniae in neonates

D Yin, D Dong, K Li, L Zhang, J Liang… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Five OXA-232 carbapenemase-producing Klebsiella pneumoniae isolates, belonging to the
pandemic clone sequence type 15 (ST15), were isolated from neonates and coproduced bla …

Small Klebsiella pneumoniae Plasmids: Neglected Contributors to Antibiotic Resistance

MS Ramirez, A Iriarte, R Reyes-Lamothe… - Frontiers in …, 2019 - frontiersin.org
Klebsiella pneumoniae is the causative agent of community-and, more commonly, hospital-
acquired infections. Infections caused by this bacterium have recently become more …

Co-Production of NDM-1 and OXA-232 by ST16 Klebsiella Pneumoniae, Italy, 2016

M Avolio, C Vignaroli, M Crapis… - Future Microbiology, 2017 - Taylor & Francis
Carbapenem-resistant Klebsiella pneumoniae strains, New Delhi metallo-β-lactamase-1
producers, are still rare in Italy, being endemic in Southeast Asiatic region. In October 2016 …

First report of Klebsiella oxytoca strain simultaneously producing NDM-1, IMP-4, and KPC-2 carbapenemases

J Wang, M Yuan, H Chen, X Chen, Y Jia… - Antimicrobial agents …, 2017 - Am Soc Microbiol
The nucleotide sequences of five plasmids from one Klebsiella oxytoca isolate were
determined using the PacBio RS II system. Plasmid analysis revealed that bla NDM-1 was …

Emergence of Klebsiella variicola positive for NDM-9, a variant of New Delhi metallo-β-lactamase, in an urban river in South Korea

DYW Di, J Jang, T Unno, HG Hur - Journal of Antimicrobial …, 2017 - academic.oup.com
Objectives: To examine the presence of pathogenic bacteria carrying New Delhi metallo-β-
lactamase in the environment and to characterize the genome structures of these strains …

[HTML][HTML] Distribution of β-lactamases and emergence of carbapenemases co-occurring Enterobacterales isolates with high-level antibiotic resistance identified from …

YC Chen, WY Chen, WY Hsu, HJ Tang, Y Chou… - Journal of Microbiology …, 2022 - Elsevier
Purpose In this study, we aimed to assess the geographic distribution and molecular
characteristics of β-lactamases among Enterobacterales isolates causing intra-abdominal …