Extracellular matrix (ECM) macromolecules together with a multitude of different molecules
residing in the extracellular space play a vital role in the regulation of cellular phenotype and …

Proteoglycans are a diverse group of molecules which are characterized by a central protein
backbone that is decorated with a variety of linear sulfated glycosaminoglycan side chains …

Systemic inflammation is established as part of late-stage severe lung disease, but
molecular, functional, and phenotypic changes in peripheral immune cells in early disease …

While our understanding of tumors and how to treat them has advanced significantly since
the days of Aminopterin and the radical mastectomy, cancer remains among the leading …

Background Although trimodality therapy resecting tumours followed by chemoradiotherapy
is emerged for muscle-invasive bladder cancer (MIBC), chemotherapy produces toxicities …

The role of an extracellular matrix‐(ECM‐) receptor interaction signature has not been fully
clarified in gastric cancer. This study performed comprehensive analyses on the differentially …

Abstract Purpose Circular RNAs (circRNAs) constitute a class of regulatory RNAs that are
thought to play important roles in tumor initiation and progression. Several studies have …

Lung adenocarcinoma (LUAD) patients exhibit poor prognosis, primarily due to metastasis.
Emerging studies have demonstrated that long noncoding RNAs (lncRNAs) play critical …

Mesenchymal stem/stromal cells (MSCs) represent a heterogeneous cell population
distributed throughout various tissues, demonstrating remarkable adaptability to …

Vascular endothelial cell dysfunction involving syndecan (SDC) proteoglycans contributes to
acute sepsis-associated lung injury (ALI), but the exact SDC isoform involved is unclear. We …