Experimental models of Parkinson's disease: Challenges and Opportunities

R Lal, K Chopra - European Journal of Pharmacology, 2024 - Elsevier
Parkinson's disease (PD) is a widespread neurodegenerative disorder occurs due to the
degradation of dopaminergic neurons present in the substantia nigra pars compacta (SNpc) …

Intrauterine and Neonatal Exposure to Opioids: Toxicological, Clinical, and Medico-Legal Issues

GD Albano, C La Spina, W Pitingaro, V Milazzo… - Toxics, 2023 - mdpi.com
Opioids have a rapid transplacental passage (ie, less than 60 min); furthermore, symptoms
characterize the maternal and fetal withdrawal syndrome. Opioid withdrawal significantly …

Investigating layer-by-layer films of carbon nanotubes and nickel phthalocyanine towards diquat detection

CA Zattim Jr, HS Kavazoi, CM Miyazaki, P Alessio - Scientific Reports, 2024 - nature.com
The indiscriminate use of pesticides makes us susceptible to the toxicity of these chemical
compounds, which may be present in high quantities in our food. It is crucial to develop …

Case series: Diquat poisoning with acute kidney failure, myocardial damage, and rhabdomyolysis

G Yu, J Wang, T Jian, L Shi, L Zhao, Y Li… - Frontiers in Public …, 2022 - frontiersin.org
Diquat is a herbicide that can have deleterious effects on the kidneys, liver, heart, lungs, and
central nervous system on ingestion. Diquat poisoning-associated rhabdomyolysis has …

Interpretable machine learning for the prediction of death risk in patients with acute diquat poisoning

H Li, Z Liu, W Sun, T Li, X Dong - Scientific Reports, 2024 - nature.com
The aim of this study was to develop and validate predictive models for assessing the risk of
death in patients with acute diquat (DQ) poisoning using innovative machine learning …

Clinical characteristics of survivors versus non-survivors after acute diquat poisoning: a comparative study

M Yan, H Liu, Y Yang, X Cheng, W Sun, T Ma… - Internal and emergency …, 2024 - Springer
The aim of this study was to compare the clinical characteristics between survivors and non-
survivors after acute diquat (DQ) poisoning. Patients treated in the Emergency Department …

Clinical and pathological characteristics of diquat poisoning-related acute kidney injury

Z Xia, W Liu, L Liu - Renal failure, 2023 - Taylor & Francis
Objectives Diquat has replaced paraquat in agricultural areas as a herbicide but has led to
extensive poisoning. Unlike paraquat, which targets the lungs, diquat primarily targets the …

Construction of a risk prediction model of diquat poisoning based on clinical indicators

W Qian, J Zhou, Y Ren, Y Bai, A Peng, L Lv… - Critical Reviews in …, 2024 - Taylor & Francis
This study aims to explore the clinical characteristics and prognostic factors in patients with
diquat (DQ) poisoning and to develop a clinical risk assessment model to improve diagnosis …

Protective effect and mechanism of CoQ10 in mitochondrial dysfunction in diquat‐induced renal proximal tubular injury

J Wu, Y Jia, Y Liao, D Yang, H Ren… - … of Biochemical and …, 2024 - Wiley Online Library
Abstract Coenzyme Q10 (CoQ10) plays an important role in improving mitochondrial
function and has many beneficial effects on the kidney. However, whether CoQ10 protects …

Diagnostic and prognostic value of diquat plasma concentration and complete blood count in patients with acute diquat poisoning based on random forest algorithms

H Hu, X Ke, F Zheng, M You, T Zhou… - Human & …, 2024 - journals.sagepub.com
Currently, the incidence of diquat (DQ) poisoning is increasing, and quickly predicting the
prognosis of poisoned patients is crucial for clinical treatment. In this study, a total of 84 DQ …