The release of reactive oxygen species (ROS) and the generation of oxidative stress are
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …

Neurodegenerative disorders are significantly increasing in incidence as the age of the
global population continues to climb with improved life expectancy. At present, more than 30 …

CCN4 (cellular communication network factor 4), a highly conserved, secreted cysteine-rich
matricellular protein is emerging as a key player in the development and progression of …

Nuclear factor of activated T cells 1 (NFAT1) expression has been associated with increased
migratory/invasive properties of mammary tumor-derived cell lines in vitro. It is unknown …

Acute as well as chronic disorders of the nervous system lead to significant morbidity and
mortality for millions of individuals globally. Given the ability to govern stem cell proliferation …

Plaque formation is initiated and triggered by cell death in the vascular wall, which gradually
leads to the progression of atherosclerosis. Pyroptosis is a newly discovered form of …

The core Hippo pathway module consists of a tumour‐suppressive kinase cascade that
inhibits the transcriptional coactivators Yes‐associated protein (YAP) and WW domain …

As a proliferative and restorative entity, Wnt1 inducible signaling pathway protein 1 (WISP1)
is emerging as a novel target for a number of therapeutic strategies that are relevant for …

Diabetes mellitus affects almost 350 million individuals throughout the globe resulting in
significant morbidity and mortality. Of further concern is the growing population of individuals …

Besides intrinsic changes, malignant cells also release soluble signals that reshape their
microenvironment. Among these signals is WNT1-inducible signaling pathway protein 1 …