Inhibition of alpha-glucosidase by synthetic derivatives of lupane, oleanane, ursane and dammarane triterpenoids

EF Khusnutdinova, IE Smirnova… - Natural Product …, 2016 - journals.sagepub.com
A variety of new and earlier synthesized lupane, oleanane, ursane and dammarane
triterpenoids have been investigated for their inhibitory activity against α-glucosidase. 2, 3 …

Synthesis and anticancer activity of aminopropoxytriterpenoids

GV Giniyatyllina, IE Smirnova, OB Kazakova… - Medicinal Chemistry …, 2015 - Springer
Triterpenoids with aminopropoxy groups in C-28 or C-3 and C-28 positions were
synthesized from betulin, erythrodiol, uvaol, oleantriol and betulinic acid N …

Synthesis and antimalarial activity of 3′-trifluoromethylated 1, 2, 4-trioxolanes and 1, 2, 4, 5-tetraoxane based on deoxycholic acid

EY Yamansarov, DV Kazakov, IM Natal'ya… - Steroids, 2018 - Elsevier
A series of new steroidal peroxides–3′-trifluoromethylated 1, 2, 4-trioxolanes and 1, 2, 4, 5-
tetraoxanes based on deoxycholic acid were prepared via the reactions of the Griesbaum …

One-pot synthesis of hollongdione from dipterocarpol

IE Smirnova, OB Kazakova… - Natural Product …, 2014 - journals.sagepub.com
A one-pot synthesis of a hybrid triterpenoid-steroid molecule, hollongdione (22, 23, 24, 25,
26, 27-hexanordammar-3, 20-dion), was achieved in a yield of 89%, based on the selective …

Synthesis and the antineoplastic activity of imidazolides of betulonic acid

OB Kazakova, NI Medvedeva, TV Lopatina… - Russian Journal of …, 2015 - Springer
Abstract Lupane C-28-imidazolides containing 3-oxo-, 3-hydroxyimino-, and 2-cyano-2, 3-
seco-4 (23)-ene fragments in cycle A have been synthesized. 3-3-Hydroxyimino-lup-20 (29) …

Synthesis of triterpenoid-based ring-A azepanone and gem-3-nitro-3-chloro-derivatives by ozonolysis of 3-oximino-28-oxoallobetulin under normal and acidic …

EY Yamansarov, OB Kazakova, NI Medvedeva… - Tetrahedron, 2017 - Elsevier
It was found that ozonolysis of 3-oximino-28-oxoallobetulin under normal conditions (CHCl
3, 0° C) led to the preferred formation of azepanone (lactam) ring-A (61%) and partial …

Oxidative lactonization of oleanane and ursane acids by treating with ozone

EF Husnutdinova, AN Lobov, OS Kukovinets… - Russian Journal of …, 2015 - Springer
Features of process of oxidative lactonization of 3-oxooleanolic and 3-oxoursolic acids
under treatment with ozone were established. The similarity of the processes consists in …

Oxidation of 3β-Acetoxy-21β-acetyl-20β,28-epoxy-18α,19βH-ursane into Novel gem-Chloronitro- and 1,2,4,5-tetraoxane derivatives

EY Yamansarov, EF Khusnutdinova… - Natural Product …, 2018 - journals.sagepub.com
The first oxidative transformations of 3β-acetoxy-21β-acetyl-20β, 28-epoxy-18α, 19β H-
ursane at the 21β-acetyl reaction center were performed. Ursane-type 1, 2, 4, 5-tetraoxanes …

First synthesis of steroidal 1, 2, 4-trioxolanes

EY Yamansarov, OB Kazakova, NI Medvedeva… - Russian Journal of …, 2014 - Springer
Griesbaum ozonolysis of mixtures of methyl 3-(methoxyimino)-5β-cholan-24-oate with
ketones (cyclohexanone, methyl trifluoromethyl ketone, and phenyl trifluoromethyl ketone) …

[PDF][PDF] Синтез и цитотоксичность новых производных 20-оксо-29-нор-лупанов

ЗИ Галимова, ЛЗ Тимербаева… - Доклады …, 2019 - dokbsu.bashedu.ru
Осуществлен синтез новых производных платановой кислоты полученных
модификацией С2, С3 и С30-положений тритерпенового остова. Изучение …