Overview of histone modification
Epigenetics is the epi-information beyond the DNA sequence that can be inherited from
parents to offspring. From years of studies, people have found that histone modifications …
parents to offspring. From years of studies, people have found that histone modifications …
The bivalent genome: characterization, structure, and regulation
E Blanco, M González-Ramírez, A Alcaine-Colet… - Trends in Genetics, 2020 - cell.com
An intricate molecular machinery is at the core of gene expression regulation in every cell.
During the initial stages of organismal development, the coordinated activation of diverse …
During the initial stages of organismal development, the coordinated activation of diverse …
[HTML][HTML] The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
HG Stunnenberg, S Abrignani, D Adams, M de Almeida… - Cell, 2016 - cell.com
The International Human Epigenome Consortium (IHEC) coordinates the generation of a
catalog of high-resolution reference epigenomes of major primary human cell types. The …
catalog of high-resolution reference epigenomes of major primary human cell types. The …
Promoter bivalency favors an open chromatin architecture in embryonic stem cells
In embryonic stem cells (ESCs), developmental gene promoters are characterized by their
bivalent chromatin state, with simultaneous modification by MLL2 and Polycomb complexes …
bivalent chromatin state, with simultaneous modification by MLL2 and Polycomb complexes …
Cold stress induces enhanced chromatin accessibility and bivalent histone modifications H3K4me3 and H3K27me3 of active genes in potato
Background Cold stress can greatly affect plant growth and development. Plants have
developed special systems to respond to and tolerate cold stress. While plant scientists have …
developed special systems to respond to and tolerate cold stress. While plant scientists have …
Examining the roles of H3K4 methylation states with systematically characterized antibodies
Histone post-translational modifications (PTMs) are important genomic regulators often
studied by chromatin immunoprecipitation (ChIP), whereby their locations and relative …
studied by chromatin immunoprecipitation (ChIP), whereby their locations and relative …
Epigenetic basis of lead-induced neurological disorders
T Wang, J Zhang, Y Xu - … journal of environmental research and public …, 2020 - mdpi.com
Environmental lead (Pb) exposure is closely associated with pathogenesis of a range of
neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) …
neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) …
Two contrasting classes of nucleolus-associated domains in mouse fibroblast heterochromatin
In interphase eukaryotic cells, almost all heterochromatin is located adjacent to the
nucleolus or to the nuclear lamina, thus defining nucleolus-associated domains (NADs) and …
nucleolus or to the nuclear lamina, thus defining nucleolus-associated domains (NADs) and …
Epigenomic profiling of human CD4+ T cells supports a linear differentiation model and highlights molecular regulators of memory development
The impact of epigenetics on the differentiation of memory T (Tmem) cells is poorly defined.
We generated deep epigenomes comprising genome-wide profiles of DNA methylation …
We generated deep epigenomes comprising genome-wide profiles of DNA methylation …
Annotation of chromatin states in 66 complete mouse epigenomes during development
The morphologically and functionally distinct cell types of a multicellular organism are
maintained by their unique epigenomes and gene expression programs. Phase III of the …
maintained by their unique epigenomes and gene expression programs. Phase III of the …