Recent progress in non-native nucleic acid modifications

LK McKenzie, R El-Khoury, JD Thorpe… - Chemical Society …, 2021 - pubs.rsc.org
While Nature harnesses RNA and DNA to store, read and write genetic information, the
inherent programmability, synthetic accessibility and wide functionality of these nucleic acids …

Boron cluster anions and their derivatives in complexation reactions

VV Avdeeva, EA Malinina, NT Kuznetsov - Coordination Chemistry Reviews, 2022 - Elsevier
Boron cluster anions attract the interest of chemists because of their electronic structures,
geometry, and chemical behavior. These weak coordinating ligands allow one to vary their …

Effect of Nature of Substituents on Coordination Properties of Mono- and Disubstituted Derivatives of Boron Cluster Anions [BnHn]2– (n = 10, 12) and Carboranes …

EY Matveev, VV Avdeeva, KY Zhizhin, EA Malinina… - Inorganics, 2022 - mdpi.com
This review systematizes data on the coordination ability of mono-and disubstituted
derivatives of boron cluster anions and carboranes in complexation with transition metals …

Carboranes as unique pharmacophores in antitumor medicinal chemistry

Y Chen, F Du, L Tang, J Xu, Y Zhao, X Wu, M Li… - Molecular Therapy …, 2022 - cell.com
Carborane is a carbon-boron molecular cluster that can be viewed as a 3D analog of
benzene. It features special physical and chemical properties, and thus has the potential to …

Recent advances in the synthesis of high boron-loaded nucleic acids for BNCT

DS Novopashina, MA Vorobyeva… - Frontiers in …, 2021 - frontiersin.org
Boron clusters attract considerable attention as promising therapeutic tools for boron
neutron capture therapy (BNCT). They combine high boron content with high chemical and …

Boron clusters as enhancers of RNase H activity in the smart strategy of gene silencing by antisense oligonucleotides

D Kaniowski, K Kulik, J Suwara… - International Journal of …, 2022 - mdpi.com
Boron cluster-conjugated antisense oligonucleotides (B-ASOs) have already been
developed as therapeutic agents with “two faces”, namely as potential antisense inhibitors of …

Preparing (metalla) carboranes for nanomedicine

M Gozzi, B Schwarze, E Hey‐Hawkins - ChemMedChem, 2021 - Wiley Online Library
Abstract “There's plenty of room at the bottom”(Richard Feynman, 1959): an invitation for
(metalla) carboranes to enter the (new) field of nanomedicine. For two decades, the number …

Iron (II), cobalt (II), and nickel (II) complexes with 1, 10-phenanthroline and 2, 2′-bipyridyl and the macropolyhedral borane cluster [trans-B20H18] 2-as counterion

VV Avdeeva, AS Kubasov, SE Korolenko, VI Privalov… - Polyhedron, 2022 - Elsevier
Abstract The iron (II), cobalt (II), and nickel (II) complexation with 1, 10-phenanthroline
(Phen) and 2, 2′-bipyridyl (Bipy) have been studied in the presence of the [B 20 H 18] 2 …

EGFR-targeted cellular delivery of therapeutic nucleic acids mediated by boron clusters

D Kaniowski, J Suwara, K Ebenryter-Olbińska… - International Journal of …, 2022 - mdpi.com
New boron carriers with high boron content and targeted cancer-cell delivery are considered
the first choice for boron neutron capture therapy (BNCT) for cancer treatment. Previously …

The impact of metal nanoparticles on female reproductive system: risks and opportunities

M Aloisi, G Rossi, S Colafarina, M Guido… - International journal of …, 2022 - mdpi.com
Humans have always been exposed to tiny particles via dust storms, volcanic ash, and other
natural processes, and our bodily systems are well adapted to protect us from these …