Exploring the potential of cytomegalovirus-based vectors: a review
Viral vectors have emerged as powerful tools for delivering and expressing foreign genes,
playing a pivotal role in gene therapy. Among these vectors, cytomegalovirus (CMV) stands …
playing a pivotal role in gene therapy. Among these vectors, cytomegalovirus (CMV) stands …
[HTML][HTML] Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy
TR Müller, S Jarosch, M Hammel, J Leube… - Cell Reports …, 2021 - cell.com
Adoptive transfer of T cells expressing a transgenic T cell receptor (TCR) has the potential to
revolutionize immunotherapy of infectious diseases and cancer. However, the generation of …
revolutionize immunotherapy of infectious diseases and cancer. However, the generation of …
MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination
Y Kim, X Zheng, K Eschke, MZ Chaudhry… - Cellular & Molecular …, 2022 - nature.com
Global pandemics caused by influenza or coronaviruses cause severe disruptions to public
health and lead to high morbidity and mortality. There remains a medical need for vaccines …
health and lead to high morbidity and mortality. There remains a medical need for vaccines …
Prion protein alters viral control and enhances pathology after perinatal cytomegalovirus infection
Cytomegalovirus (CMV) infection poses risks to newborns, necessitating effective therapies.
Given that the damage includes both viral infection of brain cells and immune system-related …
Given that the damage includes both viral infection of brain cells and immune system-related …
NFAT signaling is indispensable for persistent memory responses of MCMV-specific CD8+ T cells
MZ Chaudhry, L Borkner, U Kulkarni… - PLoS …, 2024 - journals.plos.org
Cytomegalovirus (CMV) induces a unique T cell response, where antigen-specific
populations do not contract, but rather inflate during viral latency. It has been proposed that …
populations do not contract, but rather inflate during viral latency. It has been proposed that …
NFAT signaling is indispensable for persistent memory responses of MCMV-specific CD8+ T cells
M Zeeshan Chaudhry, L Borkner, F Berberich-Siebelt… - bioRxiv, 2023 - biorxiv.org
Cytomegalovirus (CMV) induces a unique T-cell response, where antigen-specific
populations do not contract, but rather inflate during viral latency. It has been proposed that …
populations do not contract, but rather inflate during viral latency. It has been proposed that …
MCMV based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination
L Cicin-Sain, Y Kim, X Zheng, K Eschke, MZ Chaudhry… - 2021 - researchsquare.com
Global pandemics by influenza or coronaviruses cause severe disruptions to the public
health and lead to severe morbidity and mortality. Vaccines against these pathogens remain …
health and lead to severe morbidity and mortality. Vaccines against these pathogens remain …