Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …

Background Emergence of new variants mainly variants of concerns (VOC) is caused by
mutations in main structural proteins of severe acute respiratory syndrome coronavirus 2 …

The emergence of the SARS-CoV-2 Omicron variant is dominant in many countries
worldwide. The high number of spike mutations is responsible for the broad immune evasion …

The scientific community has been alarmed by the possible immunological evasion, higher
infectivity, and severity of disease caused by the newest variants of SARS-CoV-2. The spike …

Abstract Objectives: Intra-host SARS-CoV-2 evolution during chronic infection in
immunocompromised hosts has been suggested as being the possible trigger of the …

Theophylline (3-methyxanthine) is a historically prominent drug used to treat respiratory
diseases, alone or in combination with other drugs. The rapid onset of the COVID-19 …

Abstract SARS-CoV2 mutants B. 1.1. 7, B. 1.351, and P. 1 contain a key mutation N501Y. B.
1.135 and P. 1 lineages have another mutation, E484K. Here, we decode the effect of these …

The emergence of Omicron (B. 1.1. 529), a new Variant of Concern in the COVID-19
pandemic, while accompanied by the ongoing Delta variant infection, has once again fueled …

ABSTRACT The Coronavirus Disease 2019 (COVID-19) pandemic continues to cause
extraordinary loss of life and economic damage. Animal models of severe acute respiratory …