Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

The adaptive immune response mediated by T cells is critical for control of Mycobacterium
tuberculosis (M. tuberculosis) infection in humans. However, the M. tuberculosis antigens …

Clinical trials of vaccines against Mycobacterium tuberculosis are well under way and
results are starting to come in. Some of these results are not so encouraging, as exemplified …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

Tuberculosis (TB) poses a great challenge to immunologists, as it represents a chronic
infection characterized by persistence of the pathogen despite development of antigen …

The ability of the adaptive immune system to restrict Mycobacterium tuberculosis (Mtb) is
impeded by activated Foxp3+ regulatory T (T reg) cells. The importance of pathogen-specific …

Tumour necrosis factor (TNF) is a potent inflammatory cytokine that plays an important role
in immunity to numerous bacterial infections, including Mycobacterium tuberculosis (Mtb) …

Tuberculosis (TB) is an international public health priority and kills almost two million people
annually. TB is out of control in Africa due to increasing poverty and HIV coinfection, and …

CD4+ CD25+ regulatory T cells (Treg) play a central role in the prevention of autoimmunity
and in the control of immune responses by down-regulating the function of effector CD4+ or …

This review focuses on recent progress in our understanding of Mycobacterium tuberculosis
survival in macrophages, the interaction of M. tuberculosis with Toll-like receptors (TLRs) …