A conceptual review of rhodanine: current applications of antiviral drugs, anticancer and antimicrobial activities

SM Mousavi, M Zarei, SA Hashemi… - Artificial cells …, 2019 - Taylor & Francis
Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …

The bioactivity of thiazolidin-4-ones: A short review of the most recent studies

D Mech, A Kurowska, N Trotsko - International Journal of Molecular …, 2021 - mdpi.com
Thiazolidin-4-ones is an important heterocyclic ring system of a pharmacophore and a
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …

New phenolic derivatives of thiazolidine-2, 4-dione with antioxidant and antiradical properties: Synthesis, characterization, in vitro evaluation, and quantum studies

G Marc, A Stana, SD Oniga, A Pîrnău, L Vlase, O Oniga - Molecules, 2019 - mdpi.com
Oxidative stress has been incriminated in the physiopathology of many diseases, such as
diabetes, cancer, atherosclerosis, and cardiovascular and neurodegenerative diseases …

[HTML][HTML] Design, synthesis and antimycobacterial activity of thiazolidine-2, 4-dione-based thiosemicarbazone derivatives

N Trotsko, J Golus, P Kazimierczak, A Paneth… - Bioorganic …, 2020 - Elsevier
The two series of thiosemicarbazone derivatives with thiazolidine-2, 4-dione (TZD) core
were designed and synthesized. The antimycobacterial activity of the target compounds was …

Thiazolidin-4-one-based derivatives–Efficient tools for designing antiprotozoal agents. A review of the last decade

H Tuszewska, J Szczepański, S Mandziuk… - Bioorganic Chemistry, 2023 - Elsevier
Thiazolidin-4-one derivatives have a wide range of therapeutic implementations and clinical
significance for medicinal chemistry. This heterocyclic ring has been reported to possess a …

[HTML][HTML] Synthesis and antibacterial activity of new (2, 4-dioxothiazolidin-5-yl/ylidene) acetic acid derivatives with thiazolidine-2, 4-dione, rhodanine and 2 …

N Trotsko, U Kosikowska, A Paneth, M Wujec… - Saudi pharmaceutical …, 2018 - Elsevier
Abstract A series of new (2, 4-dioxothiazolidin-5-yl/ylidene) acetic acid derivatives with
thiazolidine-2, 4-dione, rhodanine and 2-thiohydantoin moiety (28–65) were synthesized by …

Harnessing ROS-Induced Oxidative Stress for Halting Colorectal Cancer via Thiazolidinedione-Based SOD Inhibitors

MN Abd Al Moaty, ESH El Ashry, LF Awad… - ACS …, 2022 - ACS Publications
Based on the “canonical” view of reactive oxygen species'(ROS) contribution to
carcinogenesis, ROS induce oxidative stress and promote various tumor progression …

Antioxidant activity and antibacterial evaluation of new thiazolin-4-one derivatives as potential tryptophanyl-tRNA synthetase inhibitors

A Stana, DC Vodnar, G Marc, D Benedec… - Journal of Enzyme …, 2019 - Taylor & Francis
The rapid emergence of bacterial resistance to antibiotics currently available for treating
infectious diseases requires effective antimicrobial agents with new structural profiles and …

New N-(oxazolylmethyl)-thiazolidinedione Active against Candida albicans Biofilm: Potential Als Proteins Inhibitors

G Marc, C Araniciu, SD Oniga, L Vlase, A Pîrnău… - Molecules, 2018 - mdpi.com
C. albicans is the most frequently occurring fungal pathogen, and is becoming an increasing
public health problem, especially in the context of increased microbial resistance. This …

Polyrhodanine-based nanomaterials for biomedical applications: A review

IH Hiba, JK Koh, CW Lai, SM Mousavi, IA Badruddin… - Heliyon, 2024 - cell.com
Rhodanine is a heterocyclic organic compound that has been investigated for its potential
biomedical applications, particularly in drug discovery. Rhodanine derivatives have been …