Sunlight and Vitamin D: A global perspective for health

M Wacker, MF Holick - Dermato-endocrinology, 2013 - Taylor & Francis
Vitamin D is the sunshine vitamin that has been produced on this earth for more than 500
million years. During exposure to sunlight 7-dehydrocholesterol in the skin absorbs UV B …

Comparative oncology: what dogs and other species can teach us about humans with cancer

JD Schiffman, M Breen - Philosophical Transactions of …, 2015 - royalsocietypublishing.org
Over 1.66 million humans (approx. 500/100 000 population rate) and over 4.2 million dogs
(approx. 5300/100 000 population rate) are diagnosed with cancer annually in the USA. The …

The genomic substrate for adaptive radiation in African cichlid fish

D Brawand, CE Wagner, YI Li, M Malinsky, I Keller… - Nature, 2014 - nature.com
Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great
Lakes of East Africa. To understand the molecular mechanisms underlying cichlid …

A global environmental crisis 42,000 years ago

A Cooper, CSM Turney, J Palmer, A Hogg, M McGlone… - Science, 2021 - science.org
Geological archives record multiple reversals of Earth's magnetic poles, but the global
impacts of these events, if any, remain unclear. Uncertain radiocarbon calibration has limited …

A draft sequence of the Neandertal genome

RE Green, J Krause, AW Briggs, T Maricic, U Stenzel… - science, 2010 - science.org
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …

Testing for ancient admixture between closely related populations

EY Durand, N Patterson, D Reich… - Molecular biology and …, 2011 - academic.oup.com
One enduring question in evolutionary biology is the extent of archaic admixture in the
genomes of present-day populations. In this paper, we present a test for ancient admixture …

Human skin pigmentation as an adaptation to UV radiation

NG Jablonski, G Chaplin - Proceedings of the National …, 2010 - National Acad Sciences
Human skin pigmentation is the product of two clines produced by natural selection to adjust
levels of constitutive pigmentation to levels of UV radiation (UVR). One cline was generated …

[HTML][HTML] The contribution of Neanderthals to phenotypic variation in modern humans

M Dannemann, J Kelso - The American journal of human genetics, 2017 - cell.com
Assessing the genetic contribution of Neanderthals to non-disease phenotypes in modern
humans has been difficult because of the absence of large cohorts for which common …

Vertebrate pigmentation: from underlying genes to adaptive function

JK Hubbard, JAC Uy, ME Hauber, HE Hoekstra… - Trends in Genetics, 2010 - cell.com
Animal coloration is a powerful model for studying the genetic mechanisms that determine
phenotype. Genetic crosses of laboratory mice have provided extensive information about …

Harnessing ancient genomes to study the history of human adaptation

S Marciniak, GH Perry - Nature Reviews Genetics, 2017 - nature.com
The past several years have witnessed an explosion of successful ancient human genome-
sequencing projects, with genomic-scale ancient DNA data sets now available for more than …