AMP-activated protein kinase (AMPK) is a fundamental regulator of energy metabolism,
stress resistance, and cellular proteostasis. AMPK signaling controls an integrated signaling …

Endurance training leads to a variety of adaptations at the cellular and systemic levels that
serve to minimise disruptions in whole-body homeostasis caused by exercise. These …

Chlorpyrifos (CPF) is a typical organophosphate insecticide known to has serious
toxicological effects on aquatic animals and causes many environmental contamination …

Kidney tubular epithelial cells are high energy-consuming epithelial cells that depend
mainly on fatty acid oxidation for an energy supply. AMP-activated protein kinase (AMPK) is …

The induction of apoptosis in cancer cells is a therapeutic strategy for the treatment of
cancer. In the present study, we investigated the regulatory mechanisms responsible for …

Neurons critically depend on mitochondria for ATP production and Ca2+ buffering. They are
highly compartmentalized cells and therefore a finely tuned mitochondrial network …

The AMP-activated protein kinase (AMPK) is considered a key checkpoint to ensure energy
balance in both cells and organisms. AMPK is an αβγ heterotrimer controlled by allosteric …

AMPK is a key regulator at the molecular level for maintaining energy metabolism
homeostasis. Mammalian AMPK is a heterotrimeric complex, and its catalytic α subunit …

In the present study, we investigated the role of the main intracellular energy sensor, AMP-
activated protein kinase (AMPK), in the in vitro neurotoxicity of α-synuclein (ASYN), one of …

Protein phosphorylation is a major post‐translational modification involved in cell signalling
that regulates many physiological and pathological processes. Despite their biological …