Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in
mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the …

The participation of extracellular vesicles in many cellular processes, including reproduction,
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …

Emerging additive manufacturing techniques enable investigation of the effects of pore
geometry on cell behavior and function. Here, we 3D print microporous hydrogel scaffolds to …

YTHDF2 binds and destabilizes N 6-methyladenosine (m 6 A)-modified mRNA. The extent to
which this branch of m 6 A RNA-regulatory pathway functions in vivo and contributes to …

Infertility affects~ 7% of couples of reproductive age with little change in incidence in the last
two decades. ART, as well as other interventions, have made major strides in correcting this …

BACKGROUND Extracellular vesicles (EVs) are membrane-bound vesicles, found in
biofluids, that carry and transfer regulatory molecules, such as microRNAs (miRNAs) and …

BACKGROUND In a growth phase occurring during most of folliculogenesis, the oocyte
produces and accumulates molecules and organelles that are fundamental for the …

BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …

In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this
coupling is crucial for the growth and development of competent oocytes as it mediates the …

Primary ovarian insufficiency is a subclass of ovarian dysfunction in which the cause is
within the ovary. In most cases, an unknown mechanism leads to premature exhaustion of …