Hydrogels are attractive materials for tissue engineering, but efforts to date have shown
limited ability to produce the microstructural features necessary to promote cellular self …

Advanced in vitro models of human skeletal muscle tissue are increasingly needed to model
complex developmental dynamics and disease mechanisms not recapitulated in animal …

Embryoids and organoids hold great promise for human biology and medicine. Herein, we
discuss conceptual and technological frameworks useful for developing high-fidelity …

The vertebrate body displays a segmental organization that is most conspicuous in the
periodic organization of the vertebral column and peripheral nerves. This metameric …

Background Human pluripotent stem cell‐derived muscle models show great potential for
translational research. Here, we describe developmentally inspired methods for the …

In vertebrates, the skeletal muscles of the body and their associated stem cells originate
from muscle progenitor cells, during development. The specification of the muscles of the …

Over the last few years, there has been growing interest in measuring the contractile force
(CF) of engineered muscle tissues to evaluate their functionality. However, there are still no …

The metameric organization or segmentation of the body is a striking characteristic of many
animal species, including invertebrates such as arthropods or annelids as well as …

The neuromuscular junction (NMJ) is a specialized cholinergic synaptic interface between a
motor neuron and a skeletal muscle fiber that translates presynaptic electrical impulses into …

Skeletal muscle myoblasts (iMyoblasts) were generated from human induced pluripotent
stem cells (iPSCs) using an efficient and reliable transgene-free induction and stem cell …