Neuroligin-3: a circuit-specific synapse organizer that shapes normal function and autism spectrum disorder-associated dysfunction

M Uchigashima, A Cheung, K Futai - Frontiers in Molecular …, 2021 - frontiersin.org
Chemical synapses provide a vital foundation for neuron-neuron communication and overall
brain function. By tethering closely apposed molecular machinery for presynaptic …

Autism spectrum disorders and the gastrointestinal tract: insights into mechanisms and clinical relevance

LY Hung, KG Margolis - Nature Reviews Gastroenterology & …, 2024 - nature.com
Autism spectrum disorders (ASDs) are recognized as central neurodevelopmental disorders
diagnosed by impairments in social interactions, communication and repetitive behaviours …

Intestinal barrier dysfunction and microbiota–gut–brain axis: Possible implications in the pathogenesis and treatment of autism spectrum disorder

VN Dargenio, C Dargenio, S Castellaneta… - Nutrients, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with
multifactorial etiology, characterized by impairment in two main functional areas:(1) …

Gastrointestinal dysfunction in patients and mice expressing the autism‐associated R451C mutation in neuroligin‐3

S Hosie, M Ellis, M Swaminathan… - Autism …, 2019 - Wiley Online Library
Gastrointestinal (GI) problems constitute an important comorbidity in many patients with
autism. Multiple mutations in the neuroligin family of synaptic adhesion molecules are …

Proper synaptic adhesion signaling in the control of neural circuit architecture and brain function

HY Kim, JW Um, J Ko - Progress in Neurobiology, 2021 - Elsevier
Trans-synaptic cell-adhesion molecules are critical for governing various stages of synapse
development and specifying neural circuit properties via the formation of multifarious …

Neuronal cell adhesion molecules may mediate neuroinflammation in autism spectrum disorder

M Eve, J Gandawijaya, L Yang… - Frontiers in Psychiatry, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized
by restrictive and repetitive behaviors, alongside deficits in social interaction and …

Cortical gray matter injury in encephalopathy of prematurity: link to neurodevelopmental disorders

B Fleiss, P Gressens, HB Stolp - Frontiers in Neurology, 2020 - frontiersin.org
Preterm-born infants frequently suffer from an array of neurological damage, collectively
termed encephalopathy of prematurity (EoP). They also have an increased risk of presenting …

Advances in colonic motor complexes in mice

NJ Spencer, M Costa, TJ Hibberd… - American Journal of …, 2021 - journals.physiology.org
The primary functions of the gastrointestinal (GI) tract are to absorb nutrients, water, and
electrolytes that are essential for life. This is accompanied by the capability of the GI tract to …

The enteric nervous system deficits in autism spectrum disorder

X Wang, R Tang, Z Wei, Y Zhan, J Lu, Z Li - Frontiers in Neuroscience, 2023 - frontiersin.org
Gastrointestinal (GI) disorders are common comorbidities in individuals with autism
spectrum disorder (ASD), and abnormalities in these issues have been found to be closely …

Exposure to Antibiotics and Neurodevelopmental Disorders: Could Probiotics Modulate the Gut–Brain Axis?

T Diamanti, R Prete, N Battista, A Corsetti, A De Jaco - Antibiotics, 2022 - mdpi.com
In order to develop properly, the brain requires the intricate interconnection of genetic factors
and pre-and postnatal environmental events. The gut–brain axis has recently raised …