Biological functions and therapeutic potential of lipocalin 2 in cancer

GS Santiago-Sánchez, V Pita-Grisanti… - International journal of …, 2020 - mdpi.com
Lipocalin-2 (LCN2) is a secreted glycoprotein linked to several physiological roles, including
transporting hydrophobic ligands across cell membranes, modulating immune responses …

CRABP1 in non-canonical activities of retinoic acid in health and diseases

J Nhieu, YL Lin, LN Wei - Nutrients, 2022 - mdpi.com
In this review, we discuss the emerging role of Cellular Retinoic Acid Binding Protein 1
(CRABP1) as a mediator of non-canonical activities of retinoic acid (RA) and relevance to …

NF-κB signaling activation and roles in thyroid cancers: implication of MAP3K14/NIK

F Cormier, S Housni, F Dumont, M Villard… - Oncogenesis, 2023 - nature.com
Among follicular-derived thyroid cancers (TC), those with aggressive behavior and
resistance to current treatments display poor prognosis. NF-κB signaling pathways are …

PSMA expression level predicts differentiated thyroid cancer aggressiveness and patient outcome

M Sollini, L di Tommaso, M Kirienko, C Piombo… - EJNMMI research, 2019 - Springer
Background Prostate-specific membrane antigen (PSMA) is overexpressed on the
endothelial cells of tumor neo-vessels of several solid malignancies, including differentiated …

MicroRNA‐524‐5p suppresses the progression of papillary thyroid carcinoma cells via targeting on FOXE1 and ITGA3 in cell autophagy and cycling pathways

H Liu, X Chen, T Lin, X Chen, J Yan… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs are beneficial for cancer therapy as they can simultaneously downregulate
multiple targets involved in diverse biological pathways related to tumor development. In …

[HTML][HTML] NF-κB in Thyroid Cancer: An Update

E Crescenzi, A Leonardi, F Pacifico - International Journal of Molecular …, 2024 - mdpi.com
The dysregulated NF-κB basal activity is a common feature of human thyroid carcinomas,
especially in poorly differentiated or undifferentiated forms that, even if rare, are often …

Mapping and targeting of C1ql1-expressing cells in the mouse

S Moghimyfiroozabad, MA Paul, SM Sigoillot… - Scientific Reports, 2023 - nature.com
The C1Q complement protein C1QL1 is highly conserved in mammals where it is expressed
in various tissues including the brain. This secreted protein interacts with Brain-specific …

Identification of LCN1 as a potential biomarker for breast cancer by bioinformatic analysis

Y Yang, F Li, X Luo, B Jia, X Zhao, B Liu… - DNA and Cell …, 2019 - liebertpub.com
The biological functions of lipocalin-1 (LCN1) are involved in innate immune responses and
act as a physiological scavenger of potentially harmful lipophilic molecules. However, the …

Downregulation of cellular retinoic acid binding protein 1 fosters epithelial–mesenchymal transition in thyroid cancer

YC Hsu, WC Huang, CY Kuo, YS Li… - Molecular …, 2023 - Wiley Online Library
Cellular retinoic acid binding protein 1 (CRABP1) participates in the regulation of retinoid
signaling. Previous studies showed conflicting results regarding the role of CRABP1 in …

Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer

K Sakata, M Kanda, D Shimizu… - International …, 2022 - spandidos-publications.com
To improve the outcome of gastric cancer, novel markers that predict postoperative
prognosis are required. For this purpose, the function of cellular retinoic acid binding protein …