[HTML][HTML] Antioxidants in liver health

S Casas-Grajales, P Muriel - World journal of gastrointestinal …, 2015 - ncbi.nlm.nih.gov
Liver diseases are a worldwide medical problem because the liver is the principal
detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various …

[HTML][HTML] Plants-based medicine implication in the evolution of chronic liver diseases

M Foghis, SG Bungau, AF Bungau, CM Vesa… - Biomedicine & …, 2023 - Elsevier
Hepatic disorders are considered major health problems, due to their high incidence,
increased risk of chronicling or death and the costs involved in therapies. A large number of …

Interleukin-13 (IL-13)—a pleiotropic cytokine involved in wound healing and fibrosis

E Roeb - International Journal of Molecular Sciences, 2023 - mdpi.com
The liver, as a central metabolic organ, is systemically linked to metabolic–inflammatory
diseases. In the pathogenesis of the metabolic syndrome, inflammatory and metabolic …

Food components with antifibrotic activity and implications in prevention of liver disease

M Bae, YK Park, JY Lee - The Journal of Nutritional Biochemistry, 2018 - Elsevier
Increasing prevalence of nonalcoholic fatty liver disease (NAFLD) in parallel with the obesity
epidemic has been a major public health concern. NAFLD is the most common chronic liver …

Phytochemical profiling and anti-fibrotic activities of Plumbago indica L. and Plumbago auriculata Lam. in thioacetamide-induced liver fibrosis in rats

NM Selim, MM Melk, FR Melek, DO Saleh, M Sobeh… - Scientific Reports, 2022 - nature.com
This study aimed at investigating the chemical composition and the hepatoprotective
activities of Plumbago indica L. and P. auriculata Lam. LC–MS/MS analyses for the …

[HTML][HTML] Silymarin exerts antifungal effects via membrane-targeted mode of action by increasing permeability and inducing oxidative stress

DG Yun, DG Lee - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2017 - Elsevier
Silymarin, which is derived from the seeds of Silybum marianum, has been widely used to
prevent and treat liver disorders. It is also consumed as a dietary supplement to improve …

Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models

JK Nono, K Fu, T Mpotje, G Varrone, NA Aziz… - Scientific reports, 2020 - nature.com
Tissue fibrosis underlies the majority of human mortality to date with close to half of all
reported deaths having a fibrotic etiology. The progression of fibrosis is very complex and …

Cerium oxide nanoparticles alleviate hepatic fibrosis phenotypes in vitro

A Boey, SQ Leong, S Bhave, HK Ho - International Journal of Molecular …, 2021 - mdpi.com
Exposure to metallic nanoparticles (NPs) can result in inadvertent NP accumulation in body
tissues. While their subsequent cellular interactions can lead to unintended consequences …

The anti-inflammatory and anti-fibrotic effects of tadalafil in thioacetamide-induced liver fibrosis in rats

HM Mansour, AAA Salama… - Canadian Journal of …, 2018 - cdnsciencepub.com
Liver fibrosis is a health concern that leads to organ failure mediated via production of
inflammatory cytokines and fibrotic biomarkers. This study aimed to explore the protective …

Schistosomicidal, hepatoprotective and antioxidant activities of the N-acetyl-L-cysteine and/or praziquantel in experimental acute mansonic schistosomiasis

A de Lima Aires, HDA De Araújo, AM Galvão… - 3 Biotech, 2023 - Springer
Schistosomiasis is a tropical parasitic disease, in which the major clinical manifestation
includes hepatosplenomegaly, portal hypertension, and organs fibrosis. Clinically, treatment …