Chemoenzymatic dynamic kinetic resolution (DKR) constitutes a convenient and efficient
method to access enantiomerically pure alcohol and amine derivatives. This Perspective …

Biocatalysis has become an important tool in chemical synthesis, allowing access to
complex molecules with high levels of activity and selectivity and with low environmental …

The immobilization of enzymes as cross-linked enzyme aggregates (CLEAs) and their
applications in industrially relevant biotransformations are reviewed. The preparation of …

Many successful stories in enzyme engineering are based on the creation of randomized
diversity in large mutant libraries, containing millions to billions of enzyme variants. Methods …

The highly enantioselective kinetic resolution of homoaldols via a transacetalization reaction
has been achieved. A novel phosphoric acid, STRIP, based on a spirocyclic 1, 1 …

Numerous synthetic protocols for producing syn-diols from the corresponding alkenes have
been developed and published over recent years. It is the intent of the following tutorial …

Lipolytic enzymes catalyze the hydrolysis of ester bonds in the presence of water. In media
with low water content or in organic solvents, they can catalyze synthetic reactions such as …

Biocatalysis has emerged as a great addition to traditional chemical processes for
production of bulk chemicals and pharmaceuticals. To overcome the limitations of naturally …

The α/β-hydrolase fold enzyme superfamily is one of the largest groups of structurally related
enzymes.[1] Applications of the members of this versatile enzyme family range from the …

Abstract Furfural and 5‐hydroxymethylfurfural (HMF) are important biomass‐derived
platform chemicals that can be obtained from the dehydration of lignocellulosic sugars. A …