[HTML][HTML] Insights into regulators of p53 acetylation

M Nagasaka, C Miyajima, H Aoki, M Aoyama… - Cells, 2022 - mdpi.com
The tumor suppressor p53 is a transcription factor that regulates the expression of dozens of
target genes and diverse physiological processes. To precisely regulate the p53 network …

Mapping of scaffold/matrix attachment regions in human genome: a data mining exercise

N Narwade, S Patel, A Alam… - Nucleic acids …, 2019 - academic.oup.com
Scaffold/matrix attachment regions (S/MARs) are DNA elements that serve to
compartmentalize the chromatin into structural and functional domains. These elements are …

Long-term effects of chromatin remodeling and DNA damage in stem cells induced by environmental and dietary agents

B Bariar, CG Vestal… - Journal of Environmental …, 2013 - dl.begellhouse.com
The presence of histones acts as a barrier to protein access; thus chromatin remodeling
must occur for essential processes such as transcription and replication. In conjunction with …

[HTML][HTML] Reversible induction of translational isoforms of p53 in glucose deprivation

D Khan, A Katoch, A Das, A Sharathchandra… - Cell Death & …, 2015 - nature.com
Tumor suppressor protein p53 is a master transcription regulator, indispensable for
controlling several cellular pathways. Earlier work in our laboratory led to the identification of …

[HTML][HTML] Nuclear matrix protein SMAR1 represses c-Fos-mediated HPV18 E6 transcription through alteration of chromatin histone deacetylation

S Chakraborty, K Das, S Saha, M Mazumdar… - Journal of Biological …, 2014 - ASBMB
Matrix attachment region (MAR)-binding proteins have been implicated in the transcriptional
regulation of host as well as viral genes, but their precise role in HPV-infected cervical …

Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina

S Babu, Y Takeuchi, I Masai - Elife, 2022 - elifesciences.org
Btg3-associated nuclear protein (Banp) was originally identified as a nuclear matrix-
associated region (MAR)-binding protein and it functions as a tumor suppressor. At the …

miR-320a regulates erythroid differentiation through MAR binding protein SMAR1

SPK Mittal, J Mathai, AP Kulkarni, JK Pal… - … International Journal of …, 2013 - Elsevier
Erythropoiesis is controlled by a complex interplay of several signaling pathways and key
transcription factors, as well as microRNAs (miRNAs). MicroRNAs function as critical …

Control of apoptosis by SMAR 1

MZ Malik, MJ Alam, R Ishrat, SM Agarwal… - Molecular …, 2017 - pubs.rsc.org
The nuclear matrix associated protein SMAR1 is sensitive to p53 and acts as a stress
inducer as well as a regulator in the p53 regulatory network. Depending on the amount of …

AP‐1/C‐FOS and AP‐1/FRA2 differentially regulate early and late adipogenic differentiation of mesenchymal stem cells

GS Bose, G Kalakoti, AP Kulkarni… - Journal of Cellular …, 2024 - Wiley Online Library
Obesity is defined as an abnormal accumulation of adipose tissue in the body and is a major
global health problem due to increased morbidity and mortality. Adipose tissue is made up …

SMAR1 attenuates the stemness of osteosarcoma cells via through suppressing ABCG2 transcriptional activity

H Xu, T Liu, W Li, Q Yao - Environmental Toxicology, 2021 - Wiley Online Library
The promoting roles of the transcriptional regulator SMAR1 have been revealed in several
tumors, such as colorectal and breast cancer, however, its roles in osteosarcoma (OS) …