Domoic acid was identified as the toxin responsible for an outbreak of human poisoning that
occurred in Canada in 1987 following consumption of contaminated blue mussels [Mytilus …

There are clear age-related changes in platelet count and function, driven by changes in
hematopoietic tissue, the composition of the blood and vascular health. Platelet count …

Platelets are most recognized for their vital role as the cellular mediator of thrombosis, but
platelets also have important immune functions. Platelets initiate and sustain vascular …

In antiphospholipid syndrome (APS), antiphospholipid antibodies (aPL) binding to β2
glycoprotein I (β2GPI) induce endothelial cell–leukocyte adhesion and thrombus formation …

AMPA-subtype ionotropic glutamate receptors (AMPARs) mediate fast excitatory
neurotransmission and contribute to high cognitive processes such as learning and memory …

Genetic factors contribute to the risk of thrombotic diseases. Recent genome wide
association studies have identified genetic loci including SLC44A2 which may regulate …

As blood transitions from steady laminar flow (S-flow) in healthy arteries to disturbed flow (D-
flow) in aneurysmal arteries, platelets are subjected to external forces. Biomechanical …

We aimed to evaluate the neutrophil–lymphocyte (NLR) and platelet–lymphocyte (PLR)
ratios of inpatients and outpatients suffering from different levels of major depression. In …

Platelet receptors are how platelets interact with their environment in order to function. They
enable signals to pass to the platelet interior and change functional aspects of the platelet …

Depression is a significant cause of disability and affects millions worldwide; however,
antidepressant therapies often fail or are inadequate. Current medications for treating major …