Sex differences in cognitive impairment and Alzheimer's disease

R Li, M Singh - Frontiers in neuroendocrinology, 2014 - Elsevier
Studies have shown differences in specific cognitive ability domains and risk of Alzheimer's
disease between the men and women at later age. However it is important to know that sex …

Neurodegenerative diseases: Regenerative mechanisms and novel therapeutic approaches

R Hussain, H Zubair, S Pursell, M Shahab - Brain sciences, 2018 - mdpi.com
Regeneration refers to regrowth of tissue in the central nervous system. It includes
generation of new neurons, glia, myelin, and synapses, as well as the regaining of essential …

Male hypogonadism

S Basaria - The Lancet, 2014 - thelancet.com
Male hypogonadism is a clinical syndrome that results from failure to produce physiological
concentrations of testosterone, normal amounts of sperm, or both. Hypogonadism may arise …

Protective actions of sex steroid hormones in Alzheimer's disease

CJ Pike, JC Carroll, ER Rosario, AM Barron - Frontiers in …, 2009 - Elsevier
Risk for Alzheimer's disease (AD) is associated with age-related loss of sex steroid
hormones in both women and men. In post-menopausal women, the precipitous depletion of …

The benefits and risks of testosterone replacement therapy: a review

N Bassil, S Alkaade, JE Morley - Therapeutics and clinical risk …, 2009 - Taylor & Francis
Increased longevity and population aging will increase the number of men with late onset
hypogonadism. It is a common condition, but often underdiagnosed and undertreated. The …

On the effects of testosterone on brain behavioral functions

P Celec, D Ostatníková, J Hodosy - Frontiers in neuroscience, 2015 - frontiersin.org
Testosterone influences the brain via organizational and activational effects. Numerous
relevant studies on rodents and a few on humans focusing on specific behavioral and …

Sex hormones and cognition: neuroendocrine influences on memory and learning.

DK Hamson, MM Roes, LAM Galea - 2016 - open.library.ubc.ca
Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial

MH Emmelot-Vonk, HJJ Verhaar, HRN Pour, A Aleman… - Jama, 2008 - jamanetwork.com
Context Serum testosterone levels decline significantly with aging. Testosterone
supplementation to older men might beneficially affect the aging processes. ObjectiveTo …

Sex hormones and adult hippocampal neurogenesis: Regulation, implications, and potential mechanisms

R Mahmoud, SR Wainwright, LAM Galea - Frontiers in neuroendocrinology, 2016 - Elsevier
Neurogenesis within the adult hippocampus is modulated by endogenous and exogenous
factors. Here, we review the role of sex hormones in the regulation of adult hippocampal …

The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: a preliminary randomized double-blind placebo-controlled …

CC Chiu, KP Su, TC Cheng, HC Liu, CJ Chang… - Progress in Neuro …, 2008 - Elsevier
A 24-week, randomized, double-blind placebo-controlled study was carried out to test the
feasibility of using omega-3 polyunsaturated fatty acids (PUFAs) monotherapy in people with …