The many mechanisms of viral membrane fusion proteins
LJ Earp, SE Delos, HE Park, JM White - Membrane trafficking in viral …, 2005 - Springer
Every enveloped virus fuses its membrane with a host cell membrane, thereby releasing its
genome into the cytoplasm and initiating the viral replication cycle. In each case, one or a …
genome into the cytoplasm and initiating the viral replication cycle. In each case, one or a …
Influenza virus entry
M Luo - Viral molecular machines, 2012 - Springer
As all the enveloped viruses, the entry of influenza viruses includes a number of steps in
host cell infection. This chapter summarizes the current knowledge of the entry pathway and …
host cell infection. This chapter summarizes the current knowledge of the entry pathway and …
Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus
In this study, 221 phytocompounds were evaluated for activity against anti-severe acute
respiratory syndrome associated coronavirus (SARS-CoV) activities using a cell-based …
respiratory syndrome associated coronavirus (SARS-CoV) activities using a cell-based …
Antiviral strategies against influenza virus: towards new therapeutic approaches
A Loregian, B Mercorelli, G Nannetti… - Cellular and molecular …, 2014 - Springer
Influenza viruses are major human pathogens responsible for respiratory diseases affecting
millions of people worldwide and characterized by high morbidity and significant mortality …
millions of people worldwide and characterized by high morbidity and significant mortality …
An antibody that prevents the hemagglutinin low pH fusogenic transition
C Barbey-Martin, B Gigant, T Bizebard, LJ Calder… - Virology, 2002 - Elsevier
We have determined the structure of a complex of influenza hemagglutinin (HA) with an
antibody that binds simultaneously to the membrane-distal domains of two HA monomers …
antibody that binds simultaneously to the membrane-distal domains of two HA monomers …
Influenza A virus entry inhibitors targeting the hemagglutinin
J Yang, M Li, X Shen, S Liu - Viruses, 2013 - mdpi.com
Influenza A virus (IAV) has caused seasonal influenza epidemics and influenza pandemics,
which resulted in serious threat to public health and socioeconomic impacts. Until now, only …
which resulted in serious threat to public health and socioeconomic impacts. Until now, only …
Anti-influenza agents from traditional Chinese medicine
Covering: up to 2010 After new human transmissible H1N1 (swine flu) viruses were reported
in Mexico and the United States in April 2009, the World Health Organization (WHO) …
in Mexico and the United States in April 2009, the World Health Organization (WHO) …
New small molecule entry inhibitors targeting hemagglutinin-mediated influenza a virus fusion
A Basu, A Antanasijevic, M Wang, B Li, DM Mills… - Journal of …, 2014 - Am Soc Microbiol
Influenza viruses are a major public health threat worldwide, and options for antiviral therapy
are limited by the emergence of drug-resistant virus strains. The influenza virus glycoprotein …
are limited by the emergence of drug-resistant virus strains. The influenza virus glycoprotein …
Orally active fusion inhibitor of respiratory syncytial virus
C Cianci, KL Yu, K Combrink, N Sin… - Antimicrobial agents …, 2004 - Am Soc Microbiol
ABSTRACT BMS-433771 was found to be a potent inhibitor of respiratory syncytial virus
(RSV) replication in vitro. It exhibited excellent potency against multiple laboratory and …
(RSV) replication in vitro. It exhibited excellent potency against multiple laboratory and …
Strategies of development of antiviral agents directed against influenza virus replication
HP Hsieh, JTA Hsu - Current pharmaceutical design, 2007 - ingentaconnect.com
In this review, we will discuss drug design based on proven and potential anti-influenza drug
targets including viral hemagglutinin (HA), neuraminidase (NA), M2 ion channel, 3P …
targets including viral hemagglutinin (HA), neuraminidase (NA), M2 ion channel, 3P …