Animals inhabiting temperate and boreal latitudes experience marked seasonal changes in
the quality of their environments and maximize reproductive success by phasing breeding …

Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that was isolated
from the brains of Japanese quail in 2000, which inhibited luteinizing hormone release from …

Abstract Neuropeptide FF (NPFF) and Neuropeptide VF (NPVF) are part of the extended
RFamide peptide family characterized by their common arginine (R) and amidated …

RF-amide neuropeptides, with their typical Arg-Phe-NH 2 signature at their carboxyl C-
termini, belong to a lineage of peptides that spans almost the entire life tree. Throughout …

Since its discovery as a novel gonadotropin inhibitory peptide in 2000, the central and
peripheral roles played by gonadotropin-inhibiting hormone (GnIH) have been significantly …

Neurosteroids are steroids synthesized within the central nervous system either from
cholesterol or by metabolic reactions of circulating steroid hormone precursors. It has been …

The RFamide peptide family is a group of proteins that share a common C-terminal arginine–
phenylalanine–amide motif. To date, the family comprises five groups in mammals …

At the turn of the millennium, a neuropeptide with pronounced inhibitory actions on avian
pituitary gonadotrophin secretion was identified and named gonadotrophin‐inhibitory …

ABSTRACT RF‐(Arg‐Phe) related peptides (RFRP‐1 and‐3) are considered to play a role in
the seasonal regulation of reproduction; however, the effect of the peptides depends on …

Background RF-amide-related peptide-3 (RFRP-3), the mammalian ortholog of
gonadotropin-inhibiting hormone, operates as inhibitory signal for the reproductive axis …