Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

Human skin is the largest organ and serves as the first line of defense against environmental
factors. The human microbiota is defined as the total microbial community that coexists in the …

The term fibroblast has been used generally to describe spindle-shaped stromal cells of
mesenchymal origin that produce extracellular matrix, establish tissue structure, and form …

Our skin contributes critically to health via its role as a barrier tissue, carefully regulating
passage of key substrates while also providing defense against exogenous threats …

The intestinal barrier is a complex structure that allows the absorption of nutrients while
ensuring protection against intestinal pathogens and balanced immunity. The development …

Inflammatory bowel disease (IBD) is a chronic inflammatory disease typically involving the
gastrointestinal tract but not limited to it. IBD can be subdivided into Crohn's disease (CD) …

Psoriasis is a common chronic inflammatory skin disease, associated with significant
morbidity and a considerable negative impact on the patients' quality of life. The complex …

The composition of the microbial community in the intestine may influence the functions of
distant organs such as the brain, lung, and skin. These microbes can promote disease or …

ζ-Carotene is a key intermediate in the carotenoid pathway, but owing to its low content and
difficulties in isolation, its application is restricted. In this study, three genes (pnCrtE, pnCrtB …

The knee joint has long been considered a closed system. The pathological effects of joint
diseases on distant organs have not been investigated. Herein, our clinical data showed that …