Panels of informative biallelic single nucleotide polymorphisms (SNPs) have been proposed
to be an economical method to fast-track the population genetic analysis of Plasmodium …

Background: Diversity in Plasmodium falciparum poses a major threat to malaria control and
elimination interventions. This study utilized 12 polymorphic microsatellite (MS) markers and …

In their competition for hosts, parasites with antigens that are novel to the host immune
system will be at a competitive advantage. The resulting frequency-dependent selection can …

Malaria remains a major public health problem in many countries. Unlike influenza and HIV,
where diversity in immunodominant surface antigens is understood geographically to inform …

A major motivation for developing molecular methods for malaria surveillance is to measure
the impact of control interventions on the population genetics of Plasmodium falciparum as a …

The diversity of Plasmodium falciparum within human hosts requires parasite population
size be defined in terms of parasite variation rather than the number of infected hosts. To …

In high-transmission endemic regions, local populations of Plasmodium falciparum exhibit
vast diversity of the var genes encoding its major surface antigen, with each parasite …

To better understand the factors underlying the continued incidence of clinical episodes of
falciparum malaria in E-2020 countries targeting elimination, we have characterised …

Here we introduce a new endpoint ″census population size ″to evaluate the epidemiology
and control of Plasmodium falciparum infections, where the parasite, rather than the infected …

Motivation Recombination is a fundamental process in molecular evolution, and the
identification of recombinant sequences is thus of major interest. However, current methods …