In vivo small animal micro-CT using nanoparticle contrast agents

JR Ashton, JL West, CT Badea - Frontiers in pharmacology, 2015 - frontiersin.org
Computed tomography (CT) is one of the most valuable modalities for in vivo imaging
because it is fast, high-resolution, cost-effective, and non-invasive. Moreover, CT is heavily …

Micro-CT of rodents: state-of-the-art and future perspectives

DP Clark, CT Badea - Physica medica, 2014 - Elsevier
Micron-scale computed tomography (micro-CT) is an essential tool for phenotyping and for
elucidating diseases and their therapies. This work is focused on preclinical micro-CT …

In vivo small-animal imaging using micro-CT and digital subtraction angiography

CT Badea, M Drangova, DW Holdsworth… - Physics in medicine & …, 2008 - iopscience.iop.org
Small-animal imaging has a critical role in phenotyping, drug discovery and in providing a
basic understanding of mechanisms of disease. Translating imaging methods from humans …

Contrast enhanced micro-computed tomography resolves the 3-dimensional morphology of the cardiac conduction system in mammalian hearts

RS Stephenson, MR Boyett, G Hart, T Nikolaidou… - PloS one, 2012 - journals.plos.org
The general anatomy of the cardiac conduction system (CCS) has been known for 100
years, but its complex and irregular three-dimensional (3D) geometry is not so well …

Dosimetry in micro-computed tomography: a review of the measurement methods, impacts, and characterization of the quantum GX imaging system

JA Meganck, B Liu - Molecular Imaging and Biology, 2017 - Springer
Purpose X-ray micro-computed tomography (μCT) is a widely used imaging modality in
preclinical research with applications in many areas including orthopedics, pulmonology …

Estimation of mouse organ locations through registration of a statistical mouse atlas with micro-CT images

H Wang, DB Stout… - IEEE transactions on …, 2011 - ieeexplore.ieee.org
Micro-CT is widely used in preclinical studies of small animals. Due to the low soft-tissue
contrast in typical studies, segmentation of soft tissue organs from noncontrast enhanced …

Studies of a prototype linear stationary x-ray source for tomosynthesis imaging

PR Schwoebel, JM Boone, J Shao - Physics in Medicine & …, 2014 - iopscience.iop.org
A prototype linear x-ray source to implement stationary source–stationary detector
tomosynthesis (TS) imaging has been studied. Potential applications include human breast …

[HTML][HTML] Cardiac multi-scale investigation of the right and left ventricle ex vivo: a review

H Dejea, A Bonnin, AC Cook… - … diagnosis and therapy, 2020 - ncbi.nlm.nih.gov
The heart is a complex multi-scale system composed of components integrated at the
subcellular, cellular, tissue and organ levels. The myocytes, the contractile elements of the …

Ultrafast high-resolution in vivo volume-CTA of mice cerebral vessels

SJ Schambach, S Bag, V Steil, C Isaza, L Schilling… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Animal models developed in rats and mice have become
indispensable in preclinical cerebrovascular research. Points of interest include the …

Whole animal imaging

GS Sandhu, L Solorio, AM Broome… - … Systems Biology and …, 2010 - Wiley Online Library
Translational research plays a vital role in understanding the underlying pathophysiology of
human diseases, and hence development of new diagnostic and therapeutic options for …