Micron-scale computed tomography (micro-CT) is an essential tool for phenotyping and for elucidating diseases and their therapies. This work is focused on preclinical micro-CT …
Small-animal imaging has a critical role in phenotyping, drug discovery and in providing a basic understanding of mechanisms of disease. Translating imaging methods from humans …
RS Stephenson, MR Boyett, G Hart, T Nikolaidou… - PloS one, 2012 - journals.plos.org
The general anatomy of the cardiac conduction system (CCS) has been known for 100 years, but its complex and irregular three-dimensional (3D) geometry is not so well …
JA Meganck, B Liu - Molecular Imaging and Biology, 2017 - Springer
Purpose X-ray micro-computed tomography (μCT) is a widely used imaging modality in preclinical research with applications in many areas including orthopedics, pulmonology …
H Wang, DB Stout… - IEEE transactions on …, 2011 - ieeexplore.ieee.org
Micro-CT is widely used in preclinical studies of small animals. Due to the low soft-tissue contrast in typical studies, segmentation of soft tissue organs from noncontrast enhanced …
PR Schwoebel, JM Boone, J Shao - Physics in Medicine & …, 2014 - iopscience.iop.org
A prototype linear x-ray source to implement stationary source–stationary detector tomosynthesis (TS) imaging has been studied. Potential applications include human breast …
The heart is a complex multi-scale system composed of components integrated at the subcellular, cellular, tissue and organ levels. The myocytes, the contractile elements of the …
SJ Schambach, S Bag, V Steil, C Isaza, L Schilling… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Animal models developed in rats and mice have become indispensable in preclinical cerebrovascular research. Points of interest include the …
GS Sandhu, L Solorio, AM Broome… - … Systems Biology and …, 2010 - Wiley Online Library
Translational research plays a vital role in understanding the underlying pathophysiology of human diseases, and hence development of new diagnostic and therapeutic options for …