Application of starch, cellulose, and their derivatives in the development of microparticle drug-delivery systems
Micro-and nanotechnologies have been intensively studied in recent years as novel
platforms for targeting and controlling the delivery of various pharmaceutical substances …
platforms for targeting and controlling the delivery of various pharmaceutical substances …
Nanotherapeutics for pulmonary drug delivery: An emerging approach to overcome respiratory diseases
Pulmonary diseases pose an immense threat to global health. Several nanotherapeutics-
based approaches aimed to tackle pulmonary ailments in recent years. The current …
based approaches aimed to tackle pulmonary ailments in recent years. The current …
Clofazimine nanoclusters show high efficacy in experimental TB with amelioration in paradoxical lung inflammation
The rise of tuberculosis (TB) superbugs has impeded efforts to control this infectious ailment,
and new treatment options are few. Paradoxical Inflammation (PI) is another major problem …
and new treatment options are few. Paradoxical Inflammation (PI) is another major problem …
Trans-nasal brain delivery of anti-TB drugs by methyl-β-cyclodextrin microparticles show efficient mycobacterial clearance from central nervous system
Central nervous system tuberculosis (CNS-TB) is the most severe extra-pulmonary
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
Effective cerebral tuberculosis treatment via nose-to-brain transport of anti-TB drugs using mucoadhesive nano-aggregates
Central nervous system tuberculosis (CNS-TB) is a severe form of extra-pulmonary
tuberculosis with high mortality and morbidity rates. The standard treatment regimen for CNS …
tuberculosis with high mortality and morbidity rates. The standard treatment regimen for CNS …
Fat fighting liraglutide based nano-formulation to reverse obesity: design, development and animal trials
Obesity is a metabolic disease, which is one of the major causes of morbidity and mortality,
where therapeutic options are limited. Treatment of obesity is necessary as it is associated …
where therapeutic options are limited. Treatment of obesity is necessary as it is associated …
Engineered vildagliptin-loaded polymeric nanoparticles via microfluidic and spray drying for enhanced antidiabetic activity
Background Vildagliptin (VLG), an antidiabetic agent, presents a potential solution to this
widespread affliction. It exhibits notable attributes, such as a high solubility and a shorter …
widespread affliction. It exhibits notable attributes, such as a high solubility and a shorter …
Nano-based carriers for pulmonary drug delivery: A review on the available drug delivery applications and toxicity issues
In the last decade, nanocarriers have been widely used to target specific organs and
disorders of any kind. Nonetheless, the commercialization of nanocarriers for many …
disorders of any kind. Nonetheless, the commercialization of nanocarriers for many …
Targeted delivery of the metastasis-specific tumour homing TMTP1 peptide to non-small-cell lung cancer (NSCLC) using inhalable hybrid nano-assemblies
Lung cancer is one of the most fatal malignancies, with the highest death rate (∼ 19%), and
the NSCLC type accounts for∼ 85% of lung cancers. In the search for new treatments …
the NSCLC type accounts for∼ 85% of lung cancers. In the search for new treatments …
Inhalable chitosan-coated nano-assemblies potentiate niclosamide for targeted abrogation of non-small-cell lung cancer through dual modulation of autophagy and …
Lung carcinoma, particularly non-small-cell lung cancer (NSCLC), accounts for a significant
portion of cancer-related deaths, with a fatality rate of approximately 19%. Niclosamide …
portion of cancer-related deaths, with a fatality rate of approximately 19%. Niclosamide …