Bipolar disorder (BD) is a leading cause of worldwide disability among mood disorders.
Pathological mechanisms are still vastly unclear, and current treatments with conventional …

Meta-analyses of genome-wide association studies (meta-GWASs) and candidate gene
studies have identified genetic variants associated with cardiovascular diseases, metabolic …

Mood disorders and type 2 diabetes mellitus (T2DM) are prevalent conditions that often co-
occur. We reviewed the available evidence from longitudinal and Mendelian randomisation …

Objectives The study herein aimed to assess the prevalence of type 2 diabetes mellitus
(T2DM), impaired fasting glucose (IFG), as well as general and abdominal obesity in …

Research has shown an increasingly clear relationship between diabetes and a variety of
mental health issues. These include diagnosable psychiatric disorders, and other problems …

Objective: Therapeutic options are limited for treatment-resistant bipolar depression (TRBD).
Insulin resistance (IR) confers increased risk for TRBD. We investigated metformin, an …

Background There is mounting interest in the potential efficacy of low carbohydrate and very
low carbohydrate ketogenic diets in various neurological and psychiatric disorders. Aims To …

Metabolic syndrome (MetS) and its component factors, obesity, hypertension, dyslipidaemia
and insulin resistance, have shown a bidirectional relationship with the prevalence and …

Bipolar disorder affects approximately 2% of the population and is typically characterized by
recurrent episodes of mania and depression. While some patients achieve remission using …

Activated immune-inflammatory, oxidative and nitrosative stress (IO&NS) pathways and
consequent mitochondrial aberrations are involved in the pathophysiology of psychiatric …