The diversity of GABAA receptors: Pharmacological and electrophysiological properties of GABAA channel subtypes
W Hevers, H Lüddens - Molecular neurobiology, 1998 - Springer
The amino acid γ-aminobutyric-acid (GABA) prevails in the CNS as an inhibitory neurotrans-
mitter that mediates most of its effects through fast GABA-gated Cl−-channels (GABA AR) …
mitter that mediates most of its effects through fast GABA-gated Cl−-channels (GABA AR) …
From ion currents to genomic analysis: Recent advances in GABAA receptor research
LE Rabow, SJ Russek, DH Farb - Synapse, 1995 - Wiley Online Library
The γ‐aminobutyric acid type A (GABAA) receptor represents an elementary switching
mechanism integral to the functioning of the central nervous system and a locus for the …
mechanism integral to the functioning of the central nervous system and a locus for the …
Regulation of GABAA receptor function by protein kinase C phosphorylation
CABA* receptors possess consensus sequences for phosphorylation by PKC that are
located on the presumed intracellular domains of p and y2 subunits. PKC phosphorylation …
located on the presumed intracellular domains of p and y2 subunits. PKC phosphorylation …
Subunit arrangement of γ-aminobutyric acid type A receptors
SW Baumann, R Baur, E Sigel - Journal of Biological Chemistry, 2001 - ASBMB
The GABA A receptors are ligand-gated chloride channels. The subunit stoichiometry of the
receptors is controversial; four, five, or six subunits per receptor molecule have been …
receptors is controversial; four, five, or six subunits per receptor molecule have been …
Functional Modulation of GABAA Receptors by cAMP-Dependent Protein Phosphorylation
γ-Aminobutyric acidA (GABAA) receptors are ligand-gated ion channels that mediate
inhibitory synaptic transmission in the central nervous system. The role of protein …
inhibitory synaptic transmission in the central nervous system. The role of protein …
Modulation of GABAA receptors by tyrosine phosphorylation
SJ Moss, GH Gorrie, A Amato, TG Smart - Nature, 1995 - nature.com
Abstract γ-AMINOBUTYRIC acid type-A (GABAA) receptors are the major sites of fast
synaptic inhibition in the brain. They are presumed to be pentameric heteroligomers …
synaptic inhibition in the brain. They are presumed to be pentameric heteroligomers …
Ethanol sensitivity of the GABAA receptor expressed in Xenopus oocytes requires 8 amino acids contained in the γ2L subunit
KA Wafford, DM Burnett, NJ Leidenheimer, DR Burt… - Neuron, 1991 - cell.com
Expression of brain mRNA or cRNAs in Xenopus oocytes was used to determine what
subunits of the CABAA receptor are required for modulation by barbiturates …
subunits of the CABAA receptor are required for modulation by barbiturates …
Biochemical Characterization and Localization of a Non‐N‐Methyl‐D‐Aspartate Glutamate Receptor in Rat Brain
The structure and distribution of non‐N‐methyl‐D‐aspartate glutamate receptors in the rat
brain were studied using subunit‐specific antibodies that recognize the receptor subunit …
brain were studied using subunit‐specific antibodies that recognize the receptor subunit …
The γ2 subunit of the GABAA receptor is concentrated in synaptic junctions containing the α1 and β23 subunits in hippocampus, cerebellum and globus pallidus
P Somogyi, JM Fritschy, D Benke, JDB Roberts… - …, 1996 - Elsevier
The γ2 subunit is necessary for the expression of the full benzodiazepine pharmacology of
GABAA receptors and is one of the major subunits in the brain. In order to determine the …
GABAA receptors and is one of the major subunits in the brain. In order to determine the …
Differential expression of the short and long forms of the γ2 subunit of the GABAA/benzodiazepine receptors
CP Miralles, A Gutie, ZU Khan, J Vitorica… - Molecular brain …, 1994 - Elsevier
The distribution of the mRNAs encoding the γ 2S and γ 2L subunits of the GABA A receptor
in the rat brain has been revealed by in situ hybridization, northern blot and dot blot analysis …
in the rat brain has been revealed by in situ hybridization, northern blot and dot blot analysis …