Malaria is an infectious disease and a serious public health problem in the world, with 3.3
billion people in endemic areas in 100 countries and about 200 million new cases each …

Several studies have evaluated the relationship between malondialdehyde (MDA)
concentrations and Plasmodium infections; however, the findings remain inconclusive. This …

Background Liver injury is a known feature of severe malaria, but is only incidentally
investigated in uncomplicated disease. In such cases, drug-induced hepatotoxicity is often …

Malaria is a parasitic disease (caused by different Plasmodium species) that affects millions
of people worldwide. The lack of effective malaria drugs and a vaccine contributes to this …

The use of medicinal plants in the treatment of malaria is gaining global attention due to their
efficacy and cost effectiveness. This study evaluated the bioactivity-guided antiplasmodial …

Background Infection with malaria in humans involves liver cell destruction, which alters the
levels of liver enzymes and lipid profiles. A number of studies have been conducted to …

Abstract Rutin (3, 3′, 4′ 5 and 7-pentahydroxyflavone-3-rhamnoglucoside) is a flavonoid
glycoside, found in many edible plants such as buckwheat and berries. Severe malaria is an …

Abstract Background DDX39B (BAT1) encodes an RNA helicase known to regulate
expression of TNF and IL-6. Elevated levels of these two cytokines are associated with …

Plasmodium vivax-induced malaria is among the leading causes of morbidity and mortality
in sub-tropical and tropical regions and infect 2.85 billion people globally. The continual rise …

Background Malaria has continued to be a threat to man and his wellbeing, especially
Africans and Asians. New antimalarial drugs are urgently needed to mitigate malaria …